Candide-B6 Table vaginas. 100mg 6 pieces with an applicator

$1.66

Candide-B6 Table vaginas. 100mg 6 pieces with an applicator

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SKU: 1506080912 Categories: , , Tag:

Description

Composition
Active substance:
1 tablet contains: Clotrimazole – 100.0 mg.
Excipients:
Adipic acid 70.0 mg corn starch 260.0 mg Colloidal silicon dioxide 2.67 mg lactose monohydrate 483.33 mg Magnesium stearate 4.0 mg methyl parahydroxybenzoate (0.8 mg), sodium gidrokorbanat 54.67 mg , sodium carboxymethyl starch 42.0 mg povidone K – 30 12.67 mg propyl parahydroxybenzoate 0.2 mg talc 10.0 mg.
Description:
White, biconvex uncoated tablet, oval, truncated on the one hand, with a monogram «G» on one side and the sign «V6» on the other side.
Product form:
Vaginal tablets of 100 mg. 6 tablets in a strip of aluminum foil. By the Strip 1 with an applicator, and instructions for use in a cardboard box.
Contraindications
Hypersensitivity to clotrimazole and other components of the formulation; I trimester of pregnancy.
Dosage
100 mg
Indications
Genital infections caused by yeast fungi of the genus Candida and / or Trichomonas vaginalis (vulvovaginal candidiasis, trichomoniasis); genital superinfection caused by microorganisms sensitive to clotrimazole; – reorganization of the birth canal before delivery.
Interaction with other drugs
Vaginal administration of Clotrimazole reduces the effectiveness of amphotericin B and other polyene antibiotics. While the use of nystatin activity of clotrimazole could decrease.
Overdose
Use of the drug in high doses does not cause any reactions or conditions, life-threatening. In the event of an unintended drug application (orally), the following symptoms: anorexia, nausea, gastralgia, impaired liver function; rarely – drowsiness, hallucinations, pollakiuria, allergic skin reactions. No specific antidote. It is necessary to take into activated carbon. If necessary symptomatic treatment.
pharmachologic effect
Pharmacological group:
Antifungal agent.
Pharmacodynamics:
Pharmacological action – antifungal broad-spectrum topical antimicrobial, protivoprotozoynoe, trihomonatsidnoe. Antifungal effect of clotrimazole active principle (imidazole derivative) is connected with the violation of the synthesis of ergosterol, a component of fungal cell membranes that modifies membrane permeability and cause subsequent lysis of the cells. The fungicidal concentrations interacts with mitochondrial and peroxidase enzymes, resulting in increased concentrations of hydrogen peroxide up to a toxic level, which also contributes to the destruction of fungal cells.
Clotrimazole is active against the following pathogens: Blastomyces dermatitidis
Candida spp (has the same activity with nystatin)
Coccidioides immitis
Cryptococcus neoformans (Torula histolytica)
Dermatoophytes (Trichophyton, Microsporum, Epidermophyton)
Histoplasma capsulatum
Malassezia furfur
Naegleria fowleri
Nocardia spp
Paracoccidioides brasiliensis
Sporotrichum schenckii
It is effective against Gram-positive bacteria – pathogen erythrasma Corynebacterium minutissimum, as well as Staphylococcus spp, Streptococcus spp.. , Gram-negative bacteria – Bacteroides, Gardnerella vaginalis. In high concentrations active against Trichomonas vaginalis.
Pharmacokinetics:
In the application of clotrimazole intravaginally absorption of 3-10% of the administered dose. High concentrations in the vaginal secretions, and low concentrations in the blood are retained within 48-72 hours. It is rapidly metabolized in the liver to inactive metabolites.
Pregnancy and breast-feeding
Contraindications for use in the I trimester of pregnancy. The question of the advisability of the appointment of the drug in the II and III trimester should be decided individually after consultation with the doctor. In the appointment of the drug during the II and III trimester of pregnancy should take into account the ratio of the expected benefits from the appointment of the drug to the mother and the possible risk to the fetus. It is undesirable to use a vaginal applicator.
The caution – during breastfeeding (known whether clotrimazole passes into breast milk penetrates).
Conditions of supply of pharmacies
Without recipe.
side effects
Itching, burning and swelling of the mucous membrane of the vagina, vaginal discharge, headache, gastralgia, frequent urination, intercurrent cystitis, burning sensation in the penis to sexual partners, pain during sexual intercourse.
special instructions
To prevent urogenital infections necessary simultaneous treatment of sexual partners.
If trichomoniasis to more successful treatment together with Candida-6 should be used other drugs having systemic effect (e.g., metronidazole orally).
When simultaneous infection of the labia and the surrounding areas (candida vulvitis) should be further carried out by local treatment with Candide cream.
During pregnancy, vaginal tablets treatment should be carried out without an applicator.
Patients with hepatic insufficiency should periodically monitor liver function.
When the manifestation of hypersensitivity symptoms or stimulation treatment ceased.
If no effect within 6 days should confirm the diagnosis.
Be wary – lactation.
Tablets should be avoided during menstruation.
Do not use in children under 12 years.
Storage conditions
In a dry, dark place at a temperature of from 2 to 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Locally. Only for intravaginal use. Vaginal tablets administered in the evening in the vagina as deeply as possible supine under slightly bent legs, daily for 6 days for 1 vaginal tablet of 100 mg. Repeated treatment is possible after consulting a doctor. For readjustment of the birth canal before delivery recommended single administration of one tablet.
on the use of the applicator instructions: 1. Pull the plunger of the applicator until it stops. Put a vaginal applicator in the tablet; 2. Carefully insert the applicator with the tablet into the vagina as deeply as possible (preferably in a supine position with slightly bent legs); 3. Introduce the tablet in the vagina, slowly pushing the plunger of the applicator to the stop; 4. Remove the applicator; 5. After use and before reuse porshenb completely remove from the applicator, the applicator piston and rinsed with warm (not hot) soapy water and wiped dry.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Glenmark

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