Calcium D3 Nycomed Forte Table Gesves. 500mg + 400me 60 pcs lemon

$10.45

Calcium D3 Nycomed Forte Table Gesves. 500mg + 400me 60 pcs lemon

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Description

Composition
Active substance:
1 tablet contains: Calcium carbonate – 1250 mg (equivalent to elemental calcium – 500 mg) Kolekaltsiferol (vitamin D3) – 10,0 g (400 IU) as a concentrate kolekaltsiferola – 4.0 mg.
Excipients:
Sorbitol – 390 mg, lemon flavor granulate – 50.7 mg Povidone – 36.4 mg magnesium stearate – 6.00 mg Aspartame – 1.00 mg.
Description:
Round biconvex white tablets with lemon flavor. May have slight grayish blotches and uneven edges.
Product form:
Chewable Tablets (lemon), 500 mg + 400 IU. 30, 60 or 120 tablets in a bottle of high-density polyethylene, a sealed screw cap, under which there is a tear ring gasket which provides the first control opening. 1 vial together with instructions for use placed in a pile of cardboard.
Contraindications
Hypercalcemia (increased calcium concentration in blood).
Hypercalciuria (high urinary calcium).
Nephrolithiasis.
Hypervitaminosis D.
Increased sensitivity to the drug.
Hypersensitivity to soya or peanut.
Severe renal insufficiency.
Active tuberculosis.
Sarcoidosis.
The drug in the dosage form of a tablet is not used in children under the age of 3 years. Calcium-D3 Nycomed Forte comprises aspartame, which in the body is transformed to phenylalanine. Therefore, the drug should not be taken by patients with phenylketonuria. The preparation comprises sorbitol, isomalt, sucrose, and therefore its use is not recommended for patients with hereditary fructose intolerance, glucose-galactose malabsorption or sucrase-insufficiency izomaltaznoy.
Precautions: Pregnancy, lactation, renal insufficiency.
Dosage
500 mg plus 400 IU
Indications
Prevention and treatment of calcium deficiency and / or vitamin D3.
Addition to specific treatment and prevention of osteoporosis and its complications (fractures).
Interaction with other drugs
Hypercalcemia may potentiate toxic effects of cardiac glycosides while the use of calcium and vitamin D. electrocardiogram is necessary to control and the calcium content in serum. Calcium can reduce the absorption of tetracyclines from the gastrointestinal tract. Therefore, drugs of tetracycline should take no less than 2 hours before or within 4-6 hours after ingestion of Calcium-D3 Nycomed Forte. To prevent absorption of drugs bisphosphonates decrease their recommended to take at least one hour before a Calcium-D3 Nycomed Forte. Glucocorticosteroids reduce calcium absorption, so glucocorticosteroid may require increasing doses of Calcium-D3 Nycomed Forte. With simultaneous use of thiazide diuretics series increases the risk of hypercalcemia, since they increase the tubular reabsorption of calcium. With simultaneous use of thiazide diuretics should be regular monitoring of serum calcium. Calcium reduces the effectiveness of levothyroxine decrease its absorption. The period of time between doses of levothyroxine and Calcium-D3 Nycomed Forte should be at least 4 hours. Suction quinolone antibiotics group, while the application is reduced with calcium supplementation. Therefore, quinolone antibiotics group should be taken 2 hours before or 6 hours after ingestion of Calcium-D3 Nycomed Forte. Calcium salts may reduce the absorption of iron, zinc and strontium ranelate. Therefore, iron preparations, zinc or strontium ranelate should take at least two hours before or two hours after receiving Calcium – D3 Nycomed Forte. Orlistat treatment could potentially interfere with the absorption of fat-soluble vitamins (e.g., vitamin D3).
Overdose
Overdose can lead to hypervitaminosis and hypercalcaemia D. Overdose symptoms (hypercalcemia): anorexia, thirst, polyuria, muscle weakness, nausea, vomiting, constipation, abdominal pain, fatigue, bone pain, mental disorders, polydipsia, nephrocalcinosis, urolithiasis and, in severe cases, cardiac arrhythmias. Prolonged use of excessive doses (over 2500 mg calcium) – kidney damage, calcification of soft tissues. Milk-alkali syndrome (Burnett syndrome) may occur in patients with ingestion of large amounts of calcium and sucked alkali. In the event of overdosage symptoms is necessary to stop taking calcium and vitamin D3, as well as the thiazide diuretics, and cardiac glycosides, and to consult a doctor. Treatment: gastric lavage, replenishment of fluid loss, the use of loop diuretics (e.g., furosemide), glucocorticoids, calcitonin, bisphosphonates. It is necessary to control the content of electrolytes in the blood plasma, kidney function and urine output. In severe cases, the necessary measurement of central venous pressure (CVP) monitoring and electrocardiogram (ECG).
pharmachologic effect
Pharmacological group:
Calcium-phosphorus metabolism regulator.
Pharmacodynamics:
A combined preparation, which regulates the exchange of calcium and phosphorus in the body (bones, teeth, nails, hair, muscles). Decreases resorption (resorption) and increases bone density, filling the lack of calcium and vitamin D3 in the body is required for mineralization of teeth. Calcium is involved in the regulation of nerve conduction, muscle contraction, hormone and is a component of the blood coagulation system. Adequate calcium intake is particularly important in a period of growth, pregnancy and lactation. Vitamin D3 increases calcium absorption in the intestine. The use of calcium and vitamin D3 prevents the increase in the production of parathyroid hormone (PTH), which is a stimulator of increased bone resorption (leaching calcium from the bones).
Pharmacokinetics:
Calcium
Absorption: calcium usually sucked into the gastrointestinal tract is about 30% of the dose.
Distribution and metabolism: 99% of the calcium in the body is concentrated in the rigid structure of bones and teeth. The remaining 1% is in the intra- and extracellular fluids. About 50% of the total blood calcium content is in the physiologically active ionised form, of which about 10% in combination with citrate, phosphate, or other anions, the remaining 40% bound to protein, primarily albumin.
Excretion: calcium derived intestines, the kidneys and sweat glands. Renal excretion depends on glomerular filtration and tubular reabsorption of calcium.
vitamin D3
Absorption: Vitamin D3 is readily absorbed in the small intestine (about 80% of the dose).
Distribution and metabolism: Kolekaltsiferol and its metabolites circulate in the blood associated with a specific globulin. Kolekaltsiferol converted in the liver by hydroxylation to 25-gidroksikolekaltsiferola. Then converted in the kidneys to the active form 1,25-gidroksikolekaltsiferol. 1.25 gidroksikolekaltsiferol metabolite is responsible for increasing calcium absorption. Unmetabolized vitamin D3 is deposited in fat and muscle tissue.
Excretion: Vitamin D3 is derived intestines and kidneys.
Pregnancy and breast-feeding
Calcium-D3 Nycomed Forte used during pregnancy to replenish the calcium and vitamin D3 deficiency in the body. The total daily intake during pregnancy should not exceed 2500 mg calcium and 4000 IU vitamin D. Hypercalcemia amid overdose during pregnancy may have adverse effects on the developing fetus. Calcium D3 Nycomed Forte used during lactation. Calcium and vitamin D3 can penetrate into breast milk, so you need to take into account the intake of calcium and vitamin D from other sources in the mother and child.
Conditions of supply of pharmacies
Without a prescription.
side effects
The incidence of side effects of the drug is considered as follows:
Very common:> 1/10
5
Common:> 1/100, 1/1000, 1/10 000 1/10 000
Frequency unknown (can not be calculated from the available data)
Violations by the Metabolism and nutrition:
Infrequent: hypercalcemia and hypercalciuria.
Very rare: Milk-alkali syndrome (Burnett syndrome). Usually it marked only in overdose (see. Section “Overdose”).
Disorders of the gastrointestinal tract:
Rare: constipation, flatulence, nausea, abdominal pain, diarrhea, dyspepsia.
Violations of the skin and subcutaneous tissue:
Very rare: pruritus, rash, urticaria. Violations by the immune system:
Frequency unknown: hypersensitivity reactions such as angioedema or laryngeal edema.
special instructions
When long-term therapy should be monitored calcium and creatinine in serum. The observation is especially important in elderly patients with 7 simultaneous treatment with diuretics and cardiac glycosides (see. See “The interaction with other drugs and food”), and in patients with an increased tendency to form kidney stones. In case of hypercalcaemia or signs of impaired renal function should reduce the dose or stop treatment. Vitamin D3 should be used with caution in patients with renal insufficiency. In this case it is necessary to control the content of calcium and phosphate in the serum. It is also necessary to take into account the risk of soft tissue calcification. To avoid overdose, it is necessary to take into account the additional intake of vitamin D and calcium from other sources. Calcium and vitamin D3 should be used with caution in immobilized patients with osteoporosis due to the risk of hypercalcemia. The simultaneous use of antibiotics tetracycline or quinolone is usually not recommended or should be done with caution (see. See “The interaction with other drugs and food”).
Effects on ability to drive vehicles and technically complex mechanisms
There are no data regarding the effects of the drug Calcium-D3 Nycomed Forte on the ability to drive and use machines.
Storage conditions
Keep the vial tightly closed at a temperature not higher than 25 C.
Keep out of the reach of children!.
Dosing and Administration
Calcium D3 Nycomed Forte is taken orally.
The tablets can be chewed or dissolve and take into mealtime.
Prevention and treatment of calcium deficiency and / or vitamin D3.
Adults and children over 12 years – 1 tablet 2 times a day, or 2 tablets once a day.
Children from 3 to 12 years – 1 tablet per day or prescribed by a doctor.
Addition to specific treatment and prevention of osteoporosis and its complications (fractures).
Adults – 1 tablet 2 times a day, or 2 tablets once a day.
Special patient groups
Patients with hepatic impairment:
correction dose is not required.
Patients with impaired renal function:
You should not use the drug Calcium-D3 Nycomed Forte with severe renal insufficiency.
Elderly patients:
The dose is the same as for adults. It should take into account a possible reduction in creatinine clearance.
duration of treatment
When used in the prevention and treatment of calcium deficiency and / or vitamin D3 average duration of treatment not less than 4-6 weeks. The number of repeated courses is determined individually during the year. When applying for a supplement to specific treatment and prevention of osteoporosis and its complications (fractures) the duration of treatment is determined individually by the physician.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Calcium D3 Nycomed

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