Bromhexine 8 Berlin-Chemie pills 8mg 25 pc

$2.49

Bromhexine 8 Berlin-Chemie pills 8mg 25 pc

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Description

Composition
Active substance:
1 tablet contains: bromhexine hydrochloride – 8,000 mg.
Excipients:
Lactose monohydrate – 34.400 mg corn starch – 14,600 mg, gelatin – 1,800 mg colloidal silicon dioxide – 0.600 mg of magnesium stearate – 0,600 mg; sheath: sucrose – 27.704 mg Calcium carbonate – 4,326 mg, magnesium carbonate – 1,507 mg, -1.507 mg talc, Macrogol 6000 – 1,750 mg, glucose syrup – 1,639 mg, titanium dioxide (E 171) – 1.166 mg Povidone K 25 – 0.243 mg carnauba wax – 0,012 mg, quinoline yellow (E 104) – 0.146 mg.
Description:
Dragees from yellow to greenish-yellow double-convex shape with almost white core.
Product form:
Dragee 8 mg.
25 pills in blisters (blister PVC / aluminum foil).
1 blister together with instructions for use in a cardboard box.
Contraindications
Hypersensitivity to Bromhexine and other ingredients; – lactase deficiency, lactose intolerance, glucose-galactose malabsorption; – gastric ulcer and duodenal ulcer (in the acute phase); – Pregnancy (I term); – Children up to age 6 years.
Precautions – kidney and / or liver insufficiency; – in case of violation bronchial motility, accompanied by an excessive accumulation of secretions; – a tendency to gastric bleeding in the history.
Dosage
8 mg
Indications
Acute and chronic bronchopulmonary diseases accompanied by formation of high viscosity sputum (bronchial asthma, pneumonia, tracheobronchitis, obstructive bronchitis, bronchiectasis, emphysema, cystic fibrosis, tuberculosis, pneumoconiosis).
Interaction with other drugs
Bromhexine not administered simultaneously with drugs that suppress the cough center (including those containing codeine) as This makes it difficult to evacuate the liquefied sputum.
Bromhexine facilitates the penetration of antibiotics (erythromycin, cephalexin, oxytetracycline, ampicillin, amoxicillin) in bronchial secretion in the first 4-5 days of antimicrobial therapy.
Not compatible with alkaline solutions.
Overdose
Life-threatening consequences of overdose when using Bromhexine 8 Berlin-Chemie, is unknown.
Possible symptoms: nausea, vomiting, diarrhea, dyspepsia.
Treatment: artificial vomiting, gastric lavage in the first 1-2 hours after ingestion.
Because of the high degree of protein binding and elimination of a high volume of distribution bromhexine hemodialysis or forced diuresis occurs.
pharmachologic effect
Pharmacological group:
Expectorant mucolytic agent.
Pharmacodynamics:
Bromhexine 8 Berlin-Chemie has mucolytic (secretolytic) and expectorant (secretomotoric) action, as well as a weak antitussive effect. Reduces the viscosity of sputum, it activates the ciliated epithelium, mucus volume increases and improves expectoration. Stimulates the production of endogenous surfactant provides stability of alveolar cells in the breathing process. The effect appears after 2-5 days of starting treatment.
Pharmacokinetics:
When administered almost completely (99%) absorbed in the gastrointestinal tract (GIT) for 30 min. The bioavailability is about 80%. Bound to plasma proteins in 99%. It crosses the placental and blood-brain barriers. It passes into breast milk. The liver is demethylation and oxidation, is metabolised to ambroxol. The half-life is 15 hours (due to the slow reverse diffusion from the tissues). Excreted by the kidneys in the form of metabolites. In chronic renal failure (CRF) is broken off selection metabolites. Repeated application may accumulate.
Pregnancy and breast-feeding
Use of the drug during pregnancy is possible only if the expected benefit to the mother outweighs the potential risk to the fetus. Application during lactation is contraindicated.
Conditions of supply of pharmacies
Without recipe.
side effects
Usually Bromhexine 8 Berlin-Chemie is well tolerated.
In rare cases, nausea, vomiting, dyspepsia, exacerbation of gastric ulcer and duodenal ulcer, allergic reactions (rash, rhinitis, edema), dyspnea, fever and chills.
Headache, dizziness.
Increased activity of “liver” transaminases (rare).
In all forms of allergic reactions should stop taking the drug and inform the physician.
special instructions
In cases of dysmotility bronchi or with a significant volume of sputum discharge, use of the drug Bromhexine 8 Berlin-Chemie requires caution due to the risk of delays in the discharge of the respiratory tract.
In the course of treatment is recommended to drink plenty of fluids, which increases the effect of bromhexine sekretoliticheskoe.
In severe renal insufficiency should take into account the possibility of accumulation of metabolites in the liver.
In children, treatment should be combined with postural drainage and vibration massage of the chest, facilitating the removal of secretions from the bronchial tubes.
Effect on ability to drive vehicles and management mechanisms
During the period of treatment must be careful when driving and occupation of other potentially hazardous activities that require high concentration and psychomotor speed reactions.
Storage conditions
Store at a temperature not higher than 25 ° C.
Keep out of the reach of children!.
Dosing and Administration
The drug is prescribed inside after a meal, without chewing, drinking plenty of fluids.
For adults and adolescents over 14 years: 3 times daily 1-2 tablets (24-48 mg / day).
Children aged 6 to 14 years, and patients weighing less than 50 kg: take 3 times daily for 1 tablet (24 mg / day).
If any of kidney and / or liver should increase the intervals between doses, or reduce the dose. On this issue, you should consult with your doctor.
Duration of treatment is established on an individual basis and depends on the evidence and the disease. If necessary, receiving more than 4-5 days is required to consult a doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Berlin Chemie

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