Bromhexine 4 Berlin-Chemie oral solution 4mg / 5ml 60ml vial

$4.04

Bromhexine 4 Berlin-Chemie oral solution 4mg / 5ml 60ml vial

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Description

Composition
Active substance:
100 ml solution contains: bromhexine hydrochloride – 0,08 g ;.
Excipients:
Propylene glycol – 25.00 g, Sorbitol – 40.00 g, concentrate the fragrance with a smell of apricot – 0.05 g, hydrochloric acid 0.1 M (3.5%) was – 0.156 g Purified water – 49.062 g
Description:
Clear colorless slightly viscous liquid with a characteristic apricot aroma.
Product form:
Oral solution 4 mg / 5 ml.
60 or 100 ml of solution in dark glass bottles with a screw stopper, plastic or aluminum with a sealing gasket.
1 bottle complete with measuring spoon together with instructions for use in a cardboard package.
Contraindications
Increased sensitivity to the drug; peptic ulcer (in the acute phase); pregnancy (I term); lactation; congenital fructose intolerance; Children under 2 years old.
Precautions kidney and / or liver insufficiency; bronchial diseases accompanied by excessive accumulation of secretions; gastric bleeding in the history; children from 2 to 6 years old (as intended voacha).
Dosage
0.8 mg / ml
Indications
Acute and chronic bronchopulmonary diseases accompanied by formation of high viscosity sputum (tracheobronchitis, pneumonia, obstructive bronchitis, bronchiectasis, asthma, emphysema, cystic fibrosis, tuberculosis, pneumoconiosis).
Interaction with other drugs
Bromhexinum 4 Berlin-Chemie can be administered concomitantly with other drugs used in the treatment of bronchopulmonary diseases.
The combined use of the drug Bromhexine 4 Berlin-Chemie and antitussives suppressing the cough reflex (including those containing codeine), due to the weakening of the cough reflex can be a risk of stagnation.
Bromhexine 4 Berlin-Chemie promotes penetration of antibiotics (erythromycin, cephalexin, oxytetracycline, ampicillin, amoxicillin) in pulmonary tissue.
Overdose
Symptoms include nausea, vomiting and other gastrointestinal disorders.
Treatment: No specific antidote. In overdose must cause vomiting, then give the patient a liquid (water or milk). Gastric lavage recommended for 1-2 hours after ingestion.
pharmachologic effect
Pharmacological group:
Expectorant mucolytic agent.
Pharmacodynamics:
Bromhexine having mucolytic (secretolytic) and expectorant action. Reduces the viscosity of sputum; activates ciliated epithelium, increases the amount of phlegm and improves its expectoration.
Pharmacokinetics:
When administered almost completely (99%) absorbed in the gastro-intestinal tract for 30 min. Bioavailability – 80%. Bound to plasma proteins in 99%. It crosses the placental and blood-brain barriers. It passes into breast milk. The liver is demethylation and oxidation, is metabolised to ambroxol. The half-life (T1 / 2) is 16 hours (due to the slow reverse diffusion from the tissues). Excreted by the kidneys in the form of metabolites. In severe renal insufficiency T 1/2 can be increased.
Pregnancy and breast-feeding
Use of the drug in the I trimester of pregnancy is contraindicated. In II and III trimester of pregnancy, the use of the drug is possible only if the expected benefit to the mother outweighs the potential risk to the fetus. Application during lactation is contraindicated.
Conditions of supply of pharmacies
Without recipe.
side effects
The frequency is classified by category, in the case of occurrence: very common (> 1/10), common (
Violations of the digestive system:
Uncommon: nausea, vomiting, diarrhea, abdominal pain;
Violations by the immune system:
Uncommon: fever, hypersensitivity reactions (rash, angioedema, respiratory distress, pruritus, urticaria);
Very rare: anaphylactic reactions up to shock.
Violations of the skin and subcutaneous tissue disorders:
Very rare: Stevens-Johnson syndrome.
If you have side effects, the drug should be discontinued and seek medical advice.
special instructions
To maintain secretolytic drug action Bromhexine 4 Berlin-Chemie during ingestion is necessary to provide a fluid delivery system in sufficient quantity.
In cases dysmotility bronchi or use significant amount of secreted mucus (e.g., rare malignant syndrome cilia) using the product Bromhexine 4 Berlin-Chemie requires caution in connection with the risk of delay in discharge airways.
Use of the drug Bromhexine 4 Berlin-Chemie in children under the age of 2 years is possible only under medical supervision.
Note for diabetics: 5 ml (1 scoop) contains 2 g sorbitol (equivalent to 0.5 g fructose), which corresponds to 0.17 bread units.
Storage conditions
At temperatures above 25 ° C.
Drug store out of reach of children.
Dosing and Administration
Oral solution. 1 scoop contains 5 ml of solution.
Unless otherwise specified, it is recommended to observe the following dosages:
Adults and adolescents over 14 years: 3 times a day for 2-4 scoops (24-48 mg of bromhexine in the day).
Children aged 6 to 14 years, and patients weighing less than 50 kg, 3 times a day for 2 scoops (24 mg of bromhexine at night).
Children aged 2 to 6 years: 3 times a day for one measuring spoon (12 mg of bromhexine at night).
Children under 2 years: 3 times daily 1/2 measuring spoon (6 mg bromhexine per day).
By limiting renal function or severe liver disease drug should be used with longer intervals between doses, or at a reduced dose.
During the treatment it is recommended to use a sufficient amount of fluid for maintaining sekretoliticheskim action bromhexine.
Without consulting a doctor is not recommended Bromhexine 4 Berlin-Chemie more than 4-5 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Berlin Chemie

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