Belogent Cream 30g tube

Description

Composition
Active substance:
1 g of cream contains: betamethasone dipropionate – 0.640 mg (0.064%) in terms of betamethasone – 0,500 mg, and gentamicin sulfate based on gentamicin base – 1,000 mg (0.1%) ;.
Excipients:
Hlorokrezol, sodium dihydrogen phosphate monohydrate, phosphoric acid, white soft paraffin, liquid paraffin, macrogol tsetostearat, cetostearyl alcohol [60% cetyl alcohol, stearyl alcohol, 40%], sodium hydroxide, water.
Description:
A homogeneous cream white color, without mechanical impurities.
Product form:
Cream for external use.
15 g, 30 g and 40 g aluminum tube. The opening of the tube is protected by a membrane. Tube cover with plastic lid with thread and punch. Each tube together with instructions for use placed in a cardboard box.
Contraindications
Hypersensitivity patients to betamethasone, gentamicin or any of the auxiliary components of the formulation; viral skin infection, skin reactions after vaccination, open wounds, trophic ulcers, acne vulgaris, rosacea, chickenpox, cutaneous manifestations of syphilis, tuberculosis skin.
Indications
Dermatitis, allergic and inflammatory diseases of the skin with the addition of a secondary bacterial infection, or probability of its development: eczema, atopic dermatitis, atopic dermatitis, contact dermatitis (including professional), atopic dermatitis, psoriasis, lichen planus, flebotodermiya, anogenital pruritus.
Infected dermatitis, evolved due insect bites, scabies, scratching, abrasions, skin lesions and thermal diaper rash.
Pyoderma different localization (strepto-stafilodermii, impetigo, Sycosis, ecthyma). Cream Belogent® used primarily for the treatment of acute and subacute stages of inflammatory skin diseases, including accompanied by exudation.
Belogent® cream can be used in children from 1 year of care and for the shortest possible period of time. You should not use the drug to babies under the bandage, and especially under the plasticized diapers, as it increases the absorption of the drug and increases the risk of adverse reactions.
Interaction with other drugs
Belogent® drug interaction with other drugs known.
Overdose
With long-term continuous use of the drug, especially in children, in the vast surface of the skin, causing the skin to the violation of the integrity or use under occlusive dressing, it is theoretically possible to develop side effects associated with increased absorption of betamethasone and gentamicin. It should be emphasized that the probability of such events is extremely small.
Treatment: It is recommended to cancel the preparation and conduct symptomatic treatment if necessary.
pharmachologic effect
Pharmacological group:
Glucocorticosteroids for local use + aminoglycoside antibiotic.
Pharmacodynamics:
Belogent® – anti-inflammatory, antiallergic, antipruritic, antibacterial agent.
Betamethasone dipropionate – synthetic glucocorticosteroid (GCS), anti-inflammatory, antiallergic, antipruritic and vasoconstrictive action. When applied to the skin surface of the big vessels, reduces itching, reduces allocation inflammation mediators (of eosinophils and mast cells), interleukins 1 and 2, gamma interferon (from lymphocytes and macrophages), inhibits the activity of hyaluronidase, and decreases the permeability of the vascular wall. Interacts with specific receptors in the cytoplasm of cells, stimulates the synthesis of mRNA, inducing the formation of proteins, including lipocortin mediating cellular effects. Lipokortin inhibits phospholipase A2 block the release of arachidonic acid biosynthesis endoperekisey, prostaglandins, leukotrienes (contributing to the development of inflammation, allergy and other pathologic processes).
Gentamicin – an antibiotic widely spectrum aminoglycoside.
It has a bactericidal action and provides a highly efficient local treatment of primary and secondary bacterial infections of skin. Active against gram-negative bacteria: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumonia; and Gram-positive bacteria: Streptococcus spp. (Sensitive strains beta- and alpha-hemolytic streptococcus group A), Staphylococcus aureus (coagulase positive, coagulase strains and some strains producing penicillinase).
Pharmacokinetics:
When applied topically the drug at therapeutic doses transdermal absorption of active ingredients in the blood is very small. The use of occlusive dressings improves absorption of betamethasone and gentamicin, which can lead to an increased risk of side effects.
Pregnancy and breast-feeding
Local drug application Belogent® cream for external use in pregnant and lactating women are allowed under the supervision of a physician. In such cases, use of the drug should be short and, if possible, be limited to small areas of the skin. The drug should not be applied on the skin of the breast before feeding.
Conditions of supply of pharmacies
Without recipe.
side effects
Adverse events tend to be bland character. Occasionally, as in the application of other glucocorticosteroids may develop hypersensitivity reactions (itching, burning or erythema) aknepodobnye changes hypopigmentation, striae, skin atrophy, hypertrichosis, telangiectasia. In case of hypersensitivity reactions or side effects of therapy should be discontinued and seek medical advice.
special instructions
We do not recommend long (more than 4 weeks) topical application of the drug Belogent® skin on the face, since it is possible the development of rosacea, perioral dermatitis and acne.
Belogent® not be used due to the probability of getting the drug to the mucous membrane in the eye, which may contribute to the development of cataracts, glaucoma, fungal eye infections and exacerbation of herpes infection.
Some areas of the body such as armpits, inguinal folds, where there is a kind of natural occlusion, are more exposed to risk of stretch marks, so the continuous application of an ointment for topical application on the skin of these areas should be short (no more than 4 weeks).
In cases of fungal microflora of the skin, you need to use an additional antifungal agent.
Effects on ability to drive vehicles and mechanisms:
The data on the adverse effects of the drug Belogent® ointments for topical use on the ability to drive and are no mechanisms.
Storage conditions
At temperatures above 25 ° C.
Keep out of the reach of children!.
Dosing and Administration
For external use only.
Belogent® cream for topical application is applied to the affected area with a thin layer in an amount sufficient to cover the affected surfaces, twice a day, gently rubbing. In areas with thicker skin (e.g., elbows, hands and feet), and the location from which the drug is easily erased, Belogent® can be applied more often, but not more than 4 times per day. The duration of continuous treatment is usually less than 4 weeks. For the prevention of relapse in the treatment of chronic illness therapy should be continued for some time after the disappearance of all symptoms. During the year, the possibility of multiple repetition of therapy.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist