Bellalgin 10 pcs Table

$1.45

Bellalgin 10 pcs Table

Quantity:

SKU: 01000736851 Categories: , , Tag:

Description

Composition
Active substance:
1 tablet contains: belladonna leaf extract (thick belladonna extract) – 15 mg, benzocaine (benzocaine) – 250 mg, metamizole sodium (analgin) – 250 mg, sodium bicarbonate – 100 mg.
Excipients:
Potato starch, carboxymethylstarch sodium, colloidal silicon dioxide (Aerosil), talc, calcium stearate, polysorbate (Tween 80).
Description:
Round Valium tablets from light yellow to yellowish-gray with darker patches with a facet and Valium.
Product form:
Tablets.
10 tablets in blisters. 1, 2, 3 blisters together with instructions for use placed in a pile of cardboard.
Contraindications
Increased sensitivity to the drug, angle-closure glaucoma, prostatic hyperplasia, depression of blood (leukopenia, agranulocytosis, cytostatic or infectious neutropenia), severe hepatic and / or renal failure, hereditary hemolytic anemia associated with deficiency of glucose-6- phosphate dehydrogenase, bronchial asthma, induced by aspirin and other nonsteroidal anti-inflammatory drugs, pregnancy (especially I trimester in 6 Ned l), breastfeeding, children under 6 years.
Carefully.
kidney disease (pyelonephritis, glomerulonephritis including history), prolonged abuse ethanol.
Indications
The drug is used as a symptomatic treatment for diseases of the gastrointestinal tract, accompanied by increased secretion of gastric juice and spasms of smooth muscles, for the purpose of relief of heartburn, regurgitation, pain (hyperacid gastritis, peptic ulcer and 12 duodenal ulcer).
Interaction with other drugs
It enhances the effects of ethanol; simultaneous application of chlorpromazine or other derivatives of phenothiazine can lead to severe hyperthermia. Radiopaque substances, colloidal and penicillin blood substitutes should not be used during treatment metamizole sodium.
With simultaneous use of cyclosporine reduced concentration of the latter in the blood.
Metamizole, displacing connection with plasma proteins oral hypoglycemic drugs, oral anticoagulants, corticosteroids and indomethacin, increases their activity.
Phenylbutazone, barbiturates and other inducers of hepatic microsomal enzymes while the application of reduced efficiency Metamizole. The simultaneous use of other non-narcotic analgesics, tricyclic antidepressants, hormonal contraceptive means and allopurinol may lead to increased toxicity.
Sedatives and antianxiety drugs (anxiolytics) increase the analgesic action Metamizole.
Methimazole and cytotoxic agents increase the risk of leukopenia.
Codeine blockers H2-histamine receptors and enhance the effects of propranolol Metamizole.
Belladonna alkaloids, included in the formulation diminish the action of m-cholinomimetics and anticholinesterases, corticotropin, ketoconazole, anticoagulants, reduce the duration of narcosis. Potentiate arrhythmogenic effect MAO inhibitors, cardiac glycosides, clonidine, cholinolytic properties quinidine, procainamide, effects of barbiturates, agonists. antihistamines, tranquilizers. Pharmacologically incompatible with chlorpromazine, diprazinom, caffeine, caffeine-sodium benzoate, pilocarpine, neostigmine methylsulfate, bromide, thiamine.
Benzocaine reduces the antibacterial activity of sulfonamides, so their combined use is not desirable.
Sodium hydrogen reduces the absorption of doxycycline and its level in blood plasma, reduces the absorption of tetracyclines, amplifies the effect of antihypertensive drugs. Should be used with caution in patients receiving corticotropin; avoid adding solutions containing calcium, except installed compatibility is not recommended with drugs having an acid reaction, and salts of alkaloids.
Overdose
Symptoms include nausea, vomiting, gastralgia, oliguria, pyrexia, reduction in blood pressure, tachycardia, dyspnea, tinnitus, drowsiness, lightheadedness, impaired consciousness, acute agranulocytosis, hemorrhagic syndrome, acute renal and / or liver failure, seizures, paralysis of the respiratory muscles .
Treatment: gastric lavage, saline laxatives, activated carbon; carrying out forced diuresis, hemodialysis, with the development of seizures – intravenous diazepam and barbiturates fast.
pharmachologic effect
Pharmacological group:
Preparations for the treatment of functional disorders of the gastrointestinal tract. Antispasmodics in combination with analgesics. Belladonna and its derivatives in combination with analgesics.
Pharmacodynamics:
Combined preparation has antispasmodic, antacid, locally anesthetic and analgesic effect. Spasmolytic effect due to the effect of belladonna alkaloids result m-anticholinergic effect decreases the tonus of smooth muscle organs (bronchial tree, the abdominal organs, etc.) is eliminated intestinal muscle spasm, biliary tract, decreased peristalsis of the digestive secretion, and other salivary glands, develops dromotropic and positive chronotropic effect.
Local anesthetic and analgesic effect due Metamizole and benzocaine.
Sodium bicarbonate neutralizes free hydrochloric acid gastric juice (antacid effect), providing a protective effect on the gastric mucosa.
Pharmacokinetics:
Pharmacokinetics of belladonna. Well absorbed from the gastrointestinal tract (GIT). It is not known whether belladonna alkaloids into breast milk. Atropine, hyoscyamine, scopolamine cross the placenta. Atropine and hyoscyamine readily penetrate the blood-brain barrier. Belladonna alkaloids hydrolyzed to tropine and tropine acid. The kidneys and, to a lesser extent through the intestines.
Pharmacokinetics Metamizole. After ingestion metamizole sodium hydrolyzed to pharmacologically active 4N-metilaminoantipirina (IAA). MAA Bioavailability after oral administration is 90%, slightly higher than with parenteral administration. Simultaneous food intake has no significant effect on the pharmacokinetics Metamizole. Metamizole crosses the placenta. Metamizole metabolites excreted in breast milk. Metamizole metabolized to form several metabolites, the main of which is a pharmacologically-active 4Y metilaminoantipirin (IAA).
Pharmacokinetics benzocaine. Benzocaine is poorly soluble in water, so its absorption is minimal. Predominantly hydrolyzed to suck benzocaine plasma cholinesterase, a small part of it is metabolized in the liver. Metabolites are excreted by the kidneys.
The pharmacokinetics of sodium hydrogencarbonate. Antacid effect occurs rapidly, but it is short-lived. The reaction of hydrochloric acid neutralization produces carbon dioxide. Sodium bicarbonate, sucking can lead to alkalosis. Excreted by the kidneys.
Pregnancy and breast-feeding
Use during pregnancy is contraindicated.
If necessary, use during breast-feeding, breast-feeding should be discontinued.
Conditions of supply of pharmacies
Without recipe.
side effects
From the nervous system: drowsiness, dizziness, agitation, spasms.
From the urinary system: renal failure, oliguria, anuria, proteinuria, interstitial nephritis, perhaps urine staining in red.
On the part of the gastrointestinal tract: dry mouth, thirst, constipation.
On the part of the organ of vision: mydriasis, accommodation paresis, temporary blurred vision.
Cardio-vascular system: palpitations, may increase blood pressure.
From the side of hematopoiesis: agranulocytosis, leukopenia, thrombocytopenia. Allergic reactions: urticaria (including the conjunctiva and the nasal mucous membranes), angioneurotic edema, in rare cases – malignant erythema multiforme (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell’s syndrome), bronchospastic syndrome, anaphylactic shock.
special instructions
In the treatment of patients receiving cytotoxic drugs receive Metamizole should be done only under medical supervision.
In patients with atopic asthma and hay fever have an increased risk of allergic reactions.
While taking metamizole sodium agranulocytosis may develop, due to which the detection unmotivated rise in temperature, fever, sore throat, difficulty swallowing, stomatitis, and the development of phenomena of vaginitis, or proctitis, require immediate removal of the drug. With long-term use must be monitored picture peripheral blood.
It is unacceptable for the use removal of acute abdominal pain (to determine the cause).
The treatment is possible staining of urine red due to excretion of metabolites Metamizole.
Effects on ability to drive vehicles, machinery.
In applying the drug should refrain from car driving or working with other mechanisms due to the possible side effects in the nervous system, organ of vision.
Storage conditions
In the dark place at a temperature not higher than 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Inside, and food.
Adults: 1 tablet 2-3 times a day.
The maximum single dose – not more than 3 tablets, sous exact – 10 tablets.
Children older than 6 years: 1/2 tablet 1-2 times a day.
The drug is intended for the symptomatic short-term use. The duration of treatment should not exceed 3 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Russia

There are no reviews yet.

Add your review