Baneotsin powder appearance. 10g vial dispenser

Description

Composition
Active substance:
1 g of powder contains: bacitracin (in the form of zinc bacitracin) – 250 IU; neomycin (neomycin sulfate in the form) – IU 5000.
Excipients:
Powder foundation sterilized (corn starch containing no more than 2% magnesium oxide).
Description:
Fine powder color from white to yellowish.
Product form:
10 g of a powder for external use in polyethylene jars with plastic dispenser; 1 jar with instruction for use in a cardboard package.
Contraindications
Increased sensitivity to bacitracin, neomycin, aminoglycoside antibiotics series to auxiliary components of the drug; extensive lesions of the skin, since the absorption of the drug can cause ototoxic effect accompanied by hearing loss; expressed disturbances of the excretory function due to cardiac or renal failure in patients with pre-existing lesions of the vestibular and cochlear systems in cases where the possible absorption of the active components of the formulation; infections of the outer auditory meatus with perforation of the eardrum; application of powder for the treatment of eye infections; simultaneous application with systemic aminoglycoside antibiotics (because of the risk of cumulative toxicity).
Precautions: patients with decreased liver and / or kidney disease, acidosis, myasthenia gravis and other neuromuscular disorders.
Indications
Powder Baneotsin® indicated for use against infections caused by microorganisms sensitive to neomycin and / or bacitracin. -Bakterialnye skin infections limited prevalence, eg impetigo moist contagious, infected venous leg ulcers, infected eczema, diaper dermatitis, bacterial, bacterial complications of viral infections caused by Herpes simplex and Herpes zoster, including infection with varicella vesicles. -Profilaktika navel infections in newborns. -Profilaktika and treatment of infection after surgery (dermatological) procedures: Baneotsin® powder may be used for further treatment of postoperative (after excision, cautery, episiotomy, treatment of cracks in the skin, perineal and moist wound and sutures).
Interaction with other drugs
When systemic absorption of active ingredients of the drug, the simultaneous application of cephalosporin or aminoglycoside antibiotics may increase the likelihood of a number of nephrotoxic reactions.
Simultaneous application of the powder Baneotsin® diuretics such as furosemide or ethacrynic acid, can provoke oto- and nephrotoxic effect.
Absorption of the drug active components Baneotsin® phenomenon may intensify the conduction of neuromuscular blockade in patients receiving drugs, anesthetics and / or muscle relaxants.
Overdose
When used in doses significantly higher than recommended, due to the possible absorption of the active ingredients Baneotsin® powder should pay particular attention to symptoms indicative of nephrotoxicity and / or ototoxic reaction.
pharmachologic effect
Pharmacological group:
Antibiotic combination.
Pharmacodynamics:
Baneotsin® is a combined antibacterial indicated for topical application.
Baneotsin® contains two bactericidal antibiotic neomycin and bacitracin.
Bacitracin is a polypeptide antibiotic which inhibits bacterial cell membranes.
Neomycin antibiotic is an aminoglycoside, which inhibits protein synthesis bacteria.
Bacitracin is particularly active against gram-positive microorganisms, such as beta-hemolytic streptococci, staphylococci, and some gram-negative pathogens. Resistance to bacitracin is extremely rare.
Neomycin is effective against gram-positive and gram-negative microorganisms.
By using a combination of the two substances is achieved a wide range of drug action and synergy of action against a number of microorganisms, e.g., staphylococcus.
Pharmacokinetics:
The active compounds are generally not absorbed (even damaged skin), however, their high concentrations present in the skin.
Baneotsin® well tolerated. Tissue tolerance is regarded as excellent, inactivation of biological products, blood and tissue components are not marked. If the drug is applied to large areas of skin lesions, should take into account the possibility of absorption of the drug and its effects (see “Side Effects”, “Interaction with other medicinal products”, “Contraindications” and “Special instructions”).
Pregnancy and breast-feeding
Use of the drug Baneotsin® during pregnancy and lactation is possible only after consultation with your doctor if the intended benefits to the mother outweighs the potential risk to the fetus or infant. It should be remembered that neomycin, like all antibiotics aminoglycoside series, can penetrate the placental barrier. When applied systemically high dose aminoglycoside antibiotics has been described intrauterine fetal reduction hearing.
Conditions of supply of pharmacies
Without a prescription.
side effects
According to the World Health Organization (WHO), undesirable effects are classified according to their rate of development as follows: very common (> 1/10), common (by> 1/100 to
special instructions
Since the risk of toxic effects increases with a decrease in the liver and / or kidney disease, in patients with hepatic and / or renal failure should be carried out blood tests and urine together with audiometric examination before and during therapy with Baneotsin®.
When suction Baneotsin® active components of the preparation, one should pay attention to potential blockage of neuromuscular conduction, especially in patients with acidosis, myasthenia (myasthenia gravis) or other neuromuscular disorders.
Thus calcium preparations or neostigmine methylsulfate may hinder the development of such closures.
Long-term treatment should be paid attention to possible growth of resistant organisms. In such situations, should choose the appropriate treatment strategy.
In case the drug in children, patients with impaired liver and kidney function, as well as a large area of ​​the surface being treated, long-term use and deep skin lesions is recommended to consult a doctor.
Patients who developed allergy or superinfection, the drug should be canceled.
Effects on ability to drive vehicles, mechanisms: no special precautions.
Storage conditions
In the dark and dry place at a temperature below 25 C.
Keep out of the reach of children.
Dosing and Administration
Outwardly. The powder is applied thinly to the affected areas 2 – 4 times a day for adults and children with 1 day of life; where appropriate – under the bandage. Area of ​​powder coating should not exceed 1% of body surface area (which corresponds to the size of the patient’s hand).
The local application of neomycin dose for adults and children 18 years should not exceed 1 g per day (about 200 g of powder for external application) for 7 days. Patients with impaired liver / renal function, elderly dose adjustment is required.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist