Baklosan tab 10mg 50 pc

$5.51

Baklosan tab 10mg 50 pc

5 in stock

Quantity:

Description

Composition
Active substance:
1 tablet contains: baclofen 10 mg or 25 mg.
Excipients:
Lactose, potato starch, gelatin, talc, magnesium stearate, ethylcellulose.
Description:
Tablets of white color, round, biconcave. 10 mg tablets have a separatory risk.
Product form:
Tablets 10 mg, 25 mg.
50 tablets in a polypropylene jar, covered with plastic cap without tamper-evident. Jar together with instructions for use are placed in a cardboard box.
Contraindications
Hypersensitivity, epilepsy, convulsions (in Vol. H. In the anamnesis), psychoses, Parkinson’s disease, gastric ulcer and duodenal ulcers, lactase deficiency, lactose intolerance, glucose-galactose malabsorption, pregnancy and lactation, children under 3 years.
Precautions: cerebrovascular insufficiency, cerebral atherosclerosis, chronic renal failure, advanced age, children under 12 years.
Dosage
10 mg
Indications
Increased muscular tonus in multiple sclerosis, spinal cord diseases (tumors, syringomyelia, motor motoneuron disease, trauma, myelitis), cerebrovascular diseases, cerebral paralysis, meningitis, craniocerebral injury.
Interaction with other drugs
Enhances the action of drugs, central nervous system depressants, hypotensive and protivopodagricakih medicaments ethanol.
Tricyclic antidepressants increase the decrease in muscle tone; levodopa, carbidopa in combination with levodopa increases the risk of hallucinations, confusion, agitation.
Overdose
Symptoms: muscular hypotonia, respiratory center depression, confusion, coma; muscular hypotonia may persist for 72 hours after the return of consciousness. Treatment: drinking plenty of fluids, diuretics; the oppression of breath – mechanical ventilation. There is no specific antidote.
pharmachologic effect
Pharmacological group:
Muscle relaxants centrally acting.
Pharmacodynamics:
Centrally acting muscle relaxant, a derivative of the gamma-aminobutyric acid (GAMKb stimulator).
Reducing the excitability of the end sections of afferent sensitive fibers and suppressing intermediate neurons, mono- and polysynaptic inhibits the transmission of nerve impulses; reduces prestress muscle spindles. No effect on neuromuscular transmission. Neurological diseases involving spasticity of the skeletal muscles, reduces the painful spasms and clonic seizures; increases range of motion in the joints, facilitates active and passive kinesitherapy (exercise, massage, chiropractic).
Pharmacokinetics:
Absorption – high. Maximum plasma concentration is achieved 2-3 hours after dosing. Communication with plasma proteins – 30%. It crosses the placental barrier, excreted in breast milk. It is metabolized in the liver.
Excreted by the kidneys (mostly unchanged).
Conditions of supply of pharmacies
On prescription.
side effects
Depending on the frequency of occurrence of the following groups of side effects: very rare – less than 0.01%, rare – more than 0.01% and less than 0.1%, infrequent – more than 0.1% and less than 1%, frequently – more than 1 % and less than 10%, very frequent – more than 10%.
From the nervous system: very often – drowsiness, sedation; frequent – dizziness, weakness, fatigue, confusion, gait disturbance, insomnia, euphoria, depression, fatigue, ataxia, tremor, hallucinations, nightmares, nystagmus, dry mouth; rare – paresthesia, dysarthria.
Cardio-vascular system: frequent – decreased cardiac output, hypotension.
On the part of the gastrointestinal tract: very often – nausea; frequent – vomiting, constipation, diarrhea, dyspepsia; rare – abdominal pain, dysgeusia, impaired liver function.
The respiratory system: frequent – respiratory depression.
On the part of the musculoskeletal system: often – myalgia.
From the senses: common – paresis of accommodation, visual impairment.
Skin and subcutaneous tissue: often – rash, hives.
The kidneys and urinary system: frequent – polyuria, enuresis, dysuria; rare – urine retention.
Reproductive system: rare – erectile dysfunction.
General disorders: very rare – hypothermia.
In rare cases, there was an increase in spasticity, which is seen as a paradoxical reaction to the medication.
special instructions
Side effects are often transient, should be distinguished from the symptoms of the disease, about being treated: with concomitant epilepsy treatment is carried out without the abolition of antiepileptic drugs.
Patients with liver disease, and diabetes is necessary to periodically monitor the activity of “liver” transaminases, alkaline phosphatase, blood glucose concentration.
During the treatment should refrain from potentially hazardous activities related to the need for increased attention and rapid mental and motor responses.
Storage conditions
Stored in a dry place, protected from light at a temperature not higher than 25 C.
Keep out of the reach of children.
Dosing and Administration
Inside, during a meal time. In the case of missing the next reception should not take a double dose.
Adults: Initial dose of – 5 mg (1.2 10 mg tablets) 3 times a day, followed by increasing doses every 3 days by 5 mg to onset of therapeutic effect (typically up to 30-75 mg per day).
The maximum daily dose is 100 mg.
Final dose is set so as to decrease the muscle tone does not lead to excessive myasthenia not worsen motor function.
When hypersensitivity initial daily dose is 5-10 mg, followed by a slower increase.
In chronic renal failure and during hemodialysis – daily dose of – 5 mg (1/2 tablets of 10 mg).
Patients who require high doses of baclofen (75 mg to 100 mg per day), the drug should be used in tablets of 25 mg.
In patients older than 65 years the dose should be increased with caution, due to the increased risk of side effects.
Children: Initial dose of – 5 mg (2.1 10 mg tablets) 3 times a day. If necessary dosage can be cautiously increased every 3 days by 5 mg to onset of therapeutic effect.
The following doses are generally recommended:
Children from 3 to 6 years – 20-30 mg per day, from 6 to 10 years – 30-60 mg per day. For children older than 10 years, the maximum daily dose is 2.5 mg / kg body weight; initial dose – 1.5-2.0 mg / kg body weight.
Abolition of the drug was gradually (over 1-2 weeks).
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

QUINACRINE INN

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