Asparkam Table 50 pc

Description

Composition
Active substance:
1 tablet contains: magnesium tetrahydrate asparaginata – 175 mg potassium asparaginata hemihydrate – 175 mg ;.
Product form:
Tablets.
50 tablets in blisters.
Contraindications
Hypersensitivity to the drug, impaired metabolism of amino acids, hypotension. Acute and chronic renal failure, hyperkalemia, gipermagniemiya, impaired atrioventricular conduction (AV block I-III st.), Myasthenia gravis, acute metabolic acidosis, dehydration (exsicosis), hemolysis, Addison’s disease, oliguria, anuria.
Precautions: during pregnancy and lactation, the presence of hypophosphatemia, urolithiasis diathesis (associated with metabolic impairment of Ca2 +, Mg2 +, and ammonium phosphate).
Dosage
175mg + 175mg
Indications
Asparkam used in the treatment of heart failure, ischemic heart disease, hypokalemia, cardiac arrhythmias (including. H. In myocardial infarction, cardiac glycosides overdose).
Interaction with other drugs
Pharmacodynamic: combined use of potassium-sparing diuretics (triamterene, spironolactone), beta-blockers, cyclosporine, heparin, ACE inhibitors, nonsteroidal antiinflammatory drugs increases the risk of hyperkalemia until the development of arrhythmias and asystole. The use of drugs in conjunction with potassium glucocorticosteroids eliminates hypokalemia caused by the latter. Under the influence of potassium decreases the unwanted effects of cardiac glycosides. Magnesium reduces the effect of neomycin, polymyxin B, tetracycline and streptomycin. Anesthetics magnesium increase inhibitory effect of drugs on the central nervous system; while the use of atracurium besylate, decamethonium bromide and suxamethonium may increase neuromuscular blockade; calcitriol increases the magnesium content in blood plasma, calcium supplementation reduces the effect of magnesium preparations.
Enhances the negative effects batmotroponoe Drome and antiarrhythmics.
Pharmacokinetic: knitting and enveloping means reduce the absorption of the drug in the gastrointestinal tract.
Overdose
Symptoms: hyperkalemia and gipermagniemiya.
Treatment: intravenous calcium chloride; if necessary – hemodialysis and peritoneal dialysis.
pharmachologic effect
Pharmacological group:
Potassium and magnesium preparation.
Pharmacodynamics:
Asparkam a source of potassium and magnesium ions, regulates metabolic processes. The mechanism of action presumably associated with a role as a carrier asparaginata magnesium and potassium ions into the intracellular space and asparaginate participation in metabolic processes. Thus asparkam eliminates electrolyte imbalance, decreases myocardial excitability and conductivity (moderate antiarrhythmic effect).
Pharmacokinetics:
Easily absorbed when taken orally and relatively rapidly excreted by the kidneys.
Conditions of supply of pharmacies
Available without prescription.
side effects
Nausea, vomiting, diarrhea, epigastric pain (in patients with anatsidnyh gastritis or cholecystitis), atrioventricular block, paradoxical response (increase in the number of extrasystoles), hyperkalemia (nausea, vomiting, diarrhea, and paresthesia) and gipermagniemiya (facial flushing, thirst , bradycardia, decrease in blood pressure, muscle weakness, fatigue, paresis, coma, areflexia, respiratory depression, convulsions).
special instructions
Continuous monitoring indicators electrolyte homeostasis.
Storage conditions
Store at a temperature not higher than 25 C. Keep out of reach of children.
Dosing and Administration
Asparkam appointed interior, after a meal.
Usually prescribed for adults 1-2 tablets 3 times a day. The course of treatment – 3-4 weeks. repeat the course if necessary.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist