Artrozilen foam naruzhn.prim-I 15% 25g vials

Description

Composition
Active substance:
Ketoprofen lysine (ketoprofen lysine salt) 15.0 g (in terms of ketoprofen 9.375 g).
Excipients:
Polysorbate 80 4.0 g, 4.0 g of propylene glycol, 3.0 g of povidone, lavender and neroli flavor 0.2 g benzyl alcohol 0.3 g Purified water to 100 ml, a mixture of propane-butane 1.25 g .
Description:
White or almost white homogeneous foam formed during the separation of aluminum aerosol container with a nozzle-sprayer.
After the release of gas inside of the vessel is a transparent liquid, white to light yellow color.
Product form:
An aerosol for external use 15%.
25 g of aluminum aerosol formulation in a 25 ml bottle with a nozzle spray and protective cap.
1 bottle together with instructions for use in a stack of cardboard.
Contraindications
Hypersensitivity to ketoprofen and other ingredients, acetylsalicylic acid or other NSAIDs, fenofibrate, sunscreens (including history);
complete or partial combination of asthma, recurrent nasal polyposis or paranasal sinuses and intolerance to acetylsalicylic acid and other NSAIDs (including history); photosensitization reactions (history); violation of integrity of the skin (moist dermatitis, eczema, infected abrasions, wounds) at the site of the intended application;
pregnancy (III trimester), breastfeeding, children’s age (up to 6 years).
Exposure to the sun’s rays, even on cloudy days, the solarium is contraindicated during treatment and for two weeks after the last treatment.
Carefully
Hepatic porphyria (exacerbation), erosive and ulcerative lesions of the gastrointestinal tract,
severe disorders of liver and kidneys, chronic heart failure, bronchial asthma, elderly, children (6 to 12 years), pregnancy (I and II trimester).
Dosage
fifteen %
Indications
Diseases of the musculoskeletal system: rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, osteoarthritis of peripheral joints and spine, rheumatic soft tissue.
Muscular pain of rheumatic and rheumatic origin.
Trauma (including sports), soft tissue damage and joints.
The drug is intended for the symptomatic therapy reduce pain and inflammation at the time of use, does not affect the progression of the disease.
Interaction with other drugs
The drug can increase the effects of drugs that cause photosensitization.
Although the interaction with other drugs used topically or systemically,
it is unlikely in the case of prolonged treatment or treatment with high doses necessary to take into account the possibility of competition between the absorbed ketoprofen and other drugs that are easily bound to plasma proteins.
Patients taking coumarin anticoagulants, it is advisable to carry out regular monitoring of the international normalized ratio (INR).
Overdose
Very low systemic absorption of the active components of the preparation for external application makes it virtually impossible to overdose. Accidental ingestion of large amounts of the drug (20 g) may cause systemic adverse reactions typical of NSAIDs. Necessary gastric lavage, administration of activated charcoal.
pharmachologic effect
Pharmacological group:
Nonsteroidal anti-inflammatory drug (NSAID).
Pharmacodynamics:
It has a local anti-inflammatory, analgesic and antiekssudativnoe action. In an aerosol provides local therapeutic effect on affected joints, tendons, ligaments, muscles. When the articular syndrome, reduces joint pain at rest and in motion, morning stiffness and swelling of joints.
Ketoprofen does not have a catabolic effect on articular cartilage.
Pharmacokinetics:
After topical application of ketoprofen aerosol levels in the blood is less than 0.1 g / ml, and the amount of free or conjugated active agent excreted by the kidneys in the following 48 hours, equivalent to the 0.62% dose. The outer coating allows the aerosol to determine the level of ketoprofen in synovial fluid, which is equivalent to 0.2-2 mg / mL, depending on the applied dose.
Pregnancy and breast-feeding
Use of the drug in the III trimester of pregnancy is contraindicated.
Use of the drug in the I and II trimesters of pregnancy only after consultation with your doctor if the intended benefits to the mother outweighs the potential risk to the fetus.
Use of the drug in the breastfeeding period is not recommended.
Conditions of supply of pharmacies
Without recipe.
side effects
Local skin reactions, such as erythema, rash, burning, itching. Sometimes these reactions can extend beyond the zone of application of the drug and very rarely can be severe and generalized.
Allergic reactions, dermatitis, contact eczema, urticaria, bullous dermatitis, photosensitivity reaction.
Very rarely occur systemic side reactions, such as impaired renal function.
In the case of any adverse event should contact your doctor.
special instructions
The drug should only be applied to intact skin.
Avoid aerosol eyes and mucous membranes.
In order to avoid the manifestations of hypersensitivity and photosensitivity it is recommended not to expose the treated areas of skin exposed to sunlight during the course of treatment and two weeks after its completion.
After the drug is necessary to wash your hands thoroughly.
Do not use occlusive dressing.
It should immediately stop using the product in the event of any skin reaction while using sunscreens or other cosmetics containing octocrylene.
Impact on the management of vehicles and mechanisms
Information about the negative impact of the drug on the ability to drive and engage in other potentially hazardous activities that require concentration and speed of psychomotor reactions, no.
Storage conditions
Store at a temperature not higher than 25 ° C.
Keep out of the reach of children!
Dosing and Administration
Outwardly.
The drug is applied to the surface of the skin 2 times per day according to the size of the treated area and the prescribing physician gently massaging until complete absorption. In iontophoresis a drug is applied to the negative pole.
The dosage in children aged 6 to 12 years corresponds to that of adults, depending on the area of ​​application and the doctor’s recommendations.
Duration of treatment: the drug is used as in acute and chronic diseases, for a period varying from a few days to 3-4 weeks.
Before applying the invert cylinder, shake vigorously. Spraying, pressing the ribbed button.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist