Arpeflyu tab n / 50mg film about 40 pc

$10.79

Arpeflyu tab n / 50mg film about 40 pc

Quantity:

Description

Composition
Active substance:
1 tablet contains: methylphenylthiomethyl gidroksibromindol-dimethylaminomethyl-carboxylic acid ethyl ester hydrochloride monohydrate (relative to anhydrous substance) – 50 mg or 100 mg.
Excipients:
Milk sugar (lactose), microcrystalline cellulose, pregelatinized starch (starch -1500), magnesium stearate, colloidal silicon dioxide (Aerosil), povidone (polyvinylpyrrolidone, low molecular weight 12,600 +/- 2700 Medical).
shell composition: Opadry II White consisting of: talc (14.8%) macrogol (20.2%), titanium dioxide (25.0%), polyvinyl alcohol (40.0%).
Description:
Round biconvex tablets, film-coated white or almost white. View of the fracture: the shell – white or nearly white, the core – white or nearly white.
Product form:
Film-coated tablets 50 mg or 100 mg, Valium planimetric packaging.
Contraindications
Hypersensitivity to the drug, children’s age (up to 3 years). The presence of diseases such as galactose intolerance, lactase deficiency, glucose-galactose malabsorption.
Dosage
50 mg
Indications
Prevention and treatment in adults and children: influenza caused by viruses A and B, acute respiratory infections (ARI) (including complicated by bronchitis, pneumonia); secondary immunodeficiency states.
Combined therapy of chronic bronchitis, pneumonia, and recurrent herpetic infection.
Prevention of postoperative infectious complications and the normalization of immune status in adults.
Interaction with other drugs
In the appointment of other drugs, negative effects were noted.
Overdose
It is not checked.
pharmachologic effect
Pharmacological group:
Other antiviral drugs.
Pharmacological properties:
Antiviral and immunostimulatory agent.
Pharmacodynamics:
An antiviral agent, exerts immunomodulatory action and protivogrippoznoe specifically inhibits influenza viruses A and B.
Possesses properties interferon, it stimulates the humoral and cellular immune responses, phagocytic function of macrophages, increases resistance to viral infections. It prevents the development of postgrippoznyh complications, reduces the frequency of exacerbations of chronic diseases, normalizes immune parameters. Antiviral effect due to inhibition of fusion of the lipid envelope of the virus with the cell membranes on contact of the virus with the cell. Therapeutic efficacy in influenza manifested in reducing the severity of toxicity and catarrhal symptoms, fever shortening periods and the total duration of the disease. Refers to a low-toxic drugs (PM) (LD50> 4 g / kg). It does not have any negative impact on the human body when administered orally in the recommended dosages.
Pharmacokinetics:
Absorption – fast. Rapidly distributed to organs and tissues. The time to reach maximum concentration (TSmah) upon receipt of a dose of 50 mg – 1.2 hours, 100 mg -. 1.5 h metabolized in the liver. The half-life (T1 / 2) -. 17-21 h About 40% is excreted unchanged, primarily in the bile (38.9%) and the minor kidneys (0.12%). During the first day shows 90% of the administered dose.
Conditions of supply of pharmacies
Without recipe.
side effects
Allergic reactions.
special instructions
Shows no central neurotropic activity and can be used in medical practice as a preventive measure in healthy persons of various professions, including those requiring special attention and coordination of movements (transport drivers, operators, and so on).
Storage conditions
Store at a temperature not higher than 25 C. In the reach of children.
Dosing and Administration
Inside, before meals. Single dose: children from 3 to 6 years – 50 mg, from 6 to 12 – 100 mg, over 12 years and adults – 200 mg (2 tablets of 100 mg or 4 tablets of 50 mg).
For nonspecific prevention
In direct contact with patients with influenza and other acute respiratory viral infection: children from 3 to 6 years – 50 mg, from 6 to 12 years – 100 mg, over 12 years and adults – 200 mg once a day for 10-14 days.
During the epidemic of influenza and other acute respiratory viral infections, for the prevention of exacerbations of chronic bronchitis, recurrent herpetic infection: children from 3 to 6 years – 50 mg, from 6 to 12 years -100 mg, over 12 years and adults – 200 mg two times a week for 3 weeks.
Prevention of postoperative complications: children from 3 to 6 years – 50 mg, from 6 to 12 years – 100 mg, over 12 years and adults – 200 mg for 2 days before surgery, and then at 2 and 5 days after surgery.
for treatment
Influenza, SARS without other complications: children from 3 to 6 years – 50 mg, from 6 to 12 – 100 mg, over 12 years and adults – 200 mg 4 times a day (every 6 hours) for 5 days.
Flu and other acute respiratory viral infections with the development of complications (bronchitis, pneumonia, etc.): children from 3 to 6 years – 50 mg, from 6 to 12 years – 100 mg, over 12 years and adults – 200 mg 4 times a day (every 6 hours ) for 5 days then 1 single dose once a week for 4 weeks.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Lekpharm

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