Arbidol capsules. 100mg 40 pieces

$21.47

Arbidol capsules. 100mg 40 pieces

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SKU: 0298076861 Categories: , , Tags: ,

Description

Composition
Active substance:
1 capsule contains: umifenovir (umifenovir hydrochloride monohydrate, based on the hydrochloride umifenovir) – 50 mg (100 mg).
Excipients:
Potato starch 15.07 mg (30.14 mg), microcrystalline cellulose 27.88 mg (55.76 mg), colloidal silicon dioxide (Aerosil) 1.0 mg (2.0 mg), povidone (Kollidon 25) 5 05 mg (10.1 mg), calcium stearate 1.0 mg (2.0 mg);
hard gelatine capsules: titanium dioxide (E 171), quinoline yellow (E 104), coloring agent sunset yellow (E 110), methyl parahydroxybenzoate, propilparagid-roksibenzoat, acetic acid, gelatin.
Or hard gelatin capsules: titanium dioxide (E 171), quinoline yellow (E 104), coloring agent sunset yellow (E 110), gelatin.
Description:
Dosage 50 mg – 3 capsules № yellow; dosage of 100 mg – Capsules №1 white, yellow cap. The contents of capsules – a mixture comprising granules and powder from white to white with yellowish or greenish tint Valium.
Product form:
Capsules of 50 mg and 100 mg.
5 or 10 capsules in blisters. 1, 2 or 4-outline package with instructions for use in a pile of cardboard.
Contraindications
Hypersensitivity to umifenovir or any component of the formulation; children up to 3 years (50 mg dosage), children under 6 years (dosage 100 mg). The first trimester of pregnancy.
Dosage
100 mg
Indications
Prevention and treatment in adults and children: influenza A and B, and other acute respiratory viral infections.
Combined therapy of acute intestinal infection rotavirus etiology in children older than 3 years.
Combined therapy of chronic bronchitis, pneumonia, and recurrent herpetic infection.
Prevention of postoperative infectious complications.
Interaction with other drugs
In the appointment of other drugs, negative effects were noted.
Overdose
It is not checked.
pharmachologic effect
Pharmacological group:
An antiviral agent.
Pharmacodynamics:
An antiviral agent. Specifically inhibits the in vitro influenza viruses A and B (Influenzavirus A, B), including highly subtypes A (H1N1) pdm09 and A (H5N1), as well as other viruses – pathogens of acute respiratory viral infections (ARVI) (Coronavirus (Coronavirus), associated severe acute respiratory syndrome (SARS), rhinovirus (rhinovirus), adenovirus (adenovirus), respiratory syncytial virus (Pneumovirus) and parainfluenza virus (paramyxovirus)). According to the mechanism of the antiviral action relates to inhibitors of fusion (fusion), interacts with hemagglutinin of the virus and prevent fusion of lipid shell of a virus and cellular membranes. Has a moderate immunomodulatory effect, increases resistance to viral infections. It possesses interferon-inducing activity – in the study in mice induction of interferon was observed after 16 h and remained high titers of interferon in the blood up to 48 hours after administration. It stimulates cellular and humoral immune responses: it increases the number of lymphocytes in the blood, in particular T-cells (CD3), increases the number of T-helper (CD4), without affecting the level of T-suppressors (CD8), normalizes the immunoregulatory index, stimulates the phagocytic function of macrophages and increases the number of natural killer cells (NK-cells).
Therapeutic efficacy for viral infections manifest in reducing the duration and severity of the disease and its main symptoms as well as reducing the incidence of complications associated with viral infection, and bacterial exacerbations of chronic diseases. It refers to preparations of low toxicity (LD50> 4 g / kg). It does not have any negative impact on the human body when administered orally in the recommended dosages.
Pharmacokinetics. Rapidly absorbed and distributed to organs and tissues. Maximum concentration in plasma when receiving a dose of 50 mg is achieved in 1.2 hours, in a dose of 100 mg – 1.5 hours is metabolized in the liver.. The half-life is 17-21 h. About 40% is excreted unchanged, primarily in the bile (38.9%) and the minor kidneys (0.12%). During the first day shows 90% of the administered dose.
Pregnancy and breast-feeding
In animal studies there was no evidence of harmful effects on pregnancy, embryo-fetal development, labor and postnatal development. Use of the drug Arbidol® in the first trimester of pregnancy is contraindicated.
In the second and third trimester of pregnancy Arbidol® can only be used for the treatment and prevention of influenza and in the event that the anticipated benefits to the mother outweighs the potential risk to the fetus. Benefit / risk ratio is determined by the attending physician.
It is unknown whether Arbidol® passes into breast milk of lactating women. If necessary, use Arbidol® should stop breastfeeding.
Conditions of supply of pharmacies
Without a prescription.
side effects
Rarely – allergic reactions.
If any of these instructions side effects are compounded, or if you notice any other side effects not mentioned in the instructions, tell your doctor.
special instructions
It is necessary to observe the recommended instructions circuit and duration of treatment. When you miss a single dose of the drug – the missed dose should be taken as a course of reception of a preparation scheme started early and continued.
Effect on ability to drive and use machines:
Shows no central neurotropic activity and can be used in medical practice in people of different professions, including require attention and coordination of movements (transport drivers, operators, etc.).
Storage conditions
Store at a temperature not higher than 25 C. Keep out of reach of children.
Dosing and Administration
Inside, before meals.
Single dose: children from 3 to 6 years – 50 mg, from 6 to 12 – 100 mg (1 capsule of 100 mg or 2 capsules of 50 mg) over 12 years and adults – 200 mg (2 capsules of 100 mg or 4 capsules of 50 mg).
For non-specific prevention and treatment of influenza and other acute respiratory viral infections in children and adults:
Non-specific prevention:
During the epidemic of influenza and other acute respiratory viral infection: children from 3 to 6 years – 50 mg, from 6 to 12 years -100 mg, over 12 years and adults – 200 mg twice a week for 3 weeks.
In direct contact with patients with influenza and other acute respiratory viral infection: children from 3 to 6 years – 50 mg, from 6 to 12 years -100 mg, over 12 years and adults – 200 mg once a day for 10-14 days.
Treatment of influenza and other acute respiratory viral infections:
Children from 3 to 6 years – 50 mg, from 6 to 12 – 100 mg, over 12 years and adults – 200 mg 4 times a day (every 6 hours) for 5 days.
Combined therapy of acute intestinal rotavirus infections in children under 3 years from 3 to 6 years – 50 mg, from 6 to 12 years -100 mg, over 12 years – 200 mg 4 times a day (every 6 hours) for 5 days .
In the treatment of chronic bronchitis, pneumonia, recurrent herpes infection: children from 3 to 6 years – 50 mg, from 6 to 12 years -100 mg, over 12 years and adults – 200 mg 4 times a day (every 6 hours) for 5-7 days, then a single dose 2 times a week for 4 weeks.
Prevention of postoperative infectious complications: children from 3 to 6 years – 50 mg, from 6 to 12 -100 mg, over 12 years and adults – 200 mg for 2 days before surgery, then at 2 and 5 days after surgery.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Arbidol

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