Antigrippin powder for solution for adults inside pack. 3 pcs honey / lemon

Description

Composition
Active substance:
1 sachet contains: paracetamol 500 mg, chlorphenamine maleate 10 mg, ascorbic acid 200 mg.
Excipients:
Honey-lemon: sodium bicarbonate, citric acid, sorbitol, povidone, sucrose, sodium cyclamate, aspartame, acesulfame potassium, lime flavor (fruit aromatic additive “Lime”), caramel flavor, honey flavor, sodium docusate.
Chamomile: sodium bicarbonate, citric acid, sorbitol, povidone, sucrose, sodium cyclamate, aspartame, acesulfame potassium, chamomile extract, sodium docusate.
Description:
Honey-lemon powder: powder varying degrees granulation consisting of particles from white to greyish-beige color and odor. Allowed blotches of dark brown color.
Chamomile powder: powder varying degrees granulation consisting of particles from white to beige or light brown color and odor. Allowed blotches of brown.
Product form:
powder for solution for ingestion of honey-lemon and chamomile. 5,0 g of powder in a sachet made of paper / A1 / PE. According 1,2,3,4,5,6,7,8,9,10,12,15,16, 20.30 bags in a carton box with instructions for use.
Contraindications
Hypersensitivity to paracetamol, ascorbic acid, chlorphenamine or any other component of the formulation. Erosive and ulcerative lesions of the gastrointestinal tract (exacerbation). Expressed kidney and / or liver failure. Alcoholism. Closure glaucoma. Phenylketonuria. Prostatic hyperplasia. Children’s age (15 years). Pregnancy and lactation.
Precautions – kidney and / or liver failure, glucose-6-phosphate dehydrogenase deficiency, congenital hyperbilirubinemia (Gilbert syndrome, Dubin-Johnson and Rotor), viral hepatitis, alcoholic hepatitis, old age.
Indications
Infectious inflammatory diseases (SARS, influenza), accompanied by fever, chills, headache, pain in joints and muscles, nasal congestion and pain in the throat and sinuses.
Interaction with other drugs
Ascorbic acid: increases blood concentration of benzylpenicillin and tetracyclines; improves absorption of iron (ferric iron needs a divalent); can increase iron excretion while the use of deferoxamine; It increases the risk of crystalluria salicylates in the treatment of sulfonamides and short-acting, slow excretion by the kidneys acids, increases the excretion of drugs having an alkaline reaction (including alkaloids), reduces blood levels of oral contraceptives; increases total clearance ethanol; while applying action reduces the chronotropic isoprenaline; may either increase or reduce the effect of anticoagulant drugs; reduces the therapeutic action of antipsychotic drugs (neuroleptics) – phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants; simultaneous reception of barbiturates increases excretion of ascorbic acid in the urine.
Chlorphenamine maleate:
Chlorphenamine maleate increases the effects of hypnotic drugs. Antidepressants, antiparkinsonian agents, antipsychotics (phenothiazine derivatives) – increase the risk of side effects (urinary retention, dry mouth, constipation). Steroids – increases the risk of developing glaucoma. Ethanol enhances the sedative effect chlorphenamine maleate.
Paracetamol:
In the reaction of paracetamol and inducers of hepatic microsomal oxidation (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increased production of active hydroxylated metabolites, which makes the possibility of severe intoxication with small overdoses.
While taking paracetamol ethanol contributes to the development of acute pancreatitis.
Inhibitors of microsomal oxidation (including cimetidine) reduce the risk of hepatotoxicity. Simultaneous treatment with paracetamol and diflunisal increases the concentration in the blood plasma of the latter by 50%, increasing the hepatotoxicity. Simultaneous reception of barbiturates reduces the effectiveness of paracetamol.
Paracetamol reduces the effectiveness of uricosuric drugs.
Overdose
Symptoms of drug overdose due to its constituent materials. The clinical picture of acute intoxication with paracetamol develops within 6-14 hours after administration. Symptoms of chronic intoxication appear within 2-4 days after the overdose.
The symptoms of acute intoxication with paracetamol: diarrhea, loss of appetite, nausea and vomiting, abdominal discomfort and / or abdominal pain, increased sweating.
Symptoms of intoxication chlorphenamine: dizziness, agitation, sleep disturbances, depression, convulsions. Treatment: symptomatic.
pharmachologic effect
Pharmacological group:
Means to eliminate the symptoms of ARI and “cold” (non-narcotic analgesic agent + Vitamin + H1-histamine receptor blocker).
Pharmacological properties:
Combined preparation.
Paracetamol has analgesic and antipyretic activity; eliminates the headache and other types of pain, reduces fever.
Ascorbic acid (vitamin C) is involved in regulating the redox processes, carbohydrate metabolism, increases resistance.
Chlorphenamine – blocker H1-histamine receptor has anti-allergic action, facilitates respiration through the nose, reduces the feeling of nasal congestion, sneezing, lacrimation, redness and itching eyes.
Conditions of supply of pharmacies
Without recipe.
side effects
The drug was well tolerated at the recommended doses.
In rare cases, there are: the central nervous system: headache, feeling tired; by ZHKG: nausea, pain in the epigastric region; with the endocrine system: hypoglycemia (up to coma development); from the side of the blood: anemia, hemolytic anemia (particularly for patients with deficiency of glucose-6-phosphate dehydrogenase); rarely – thrombocytopenia; allergic reactions: skin rash, pruritus, urticaria, angioedema, anaphylactoid reactions (including anaphylactic shock), erythema multiforme (including Steven -Dzhonsona syndrome), toxic epidermal necrolysis (Lyell’s syndrome); Other: With hypervitaminosis, a metabolic disorder, sensation of heat, dry mouth, paresis of accommodation, urinary retention, drowsiness.
All the side effects of the drug should be reported to your doctor.
special instructions
When receiving metoclopramide, domperidone or cholestyramine also need to consult with your doctor.
With prolonged use at doses significantly higher than recommended, it increases the probability of the liver and kidney, requires monitoring of peripheral blood picture. Paracetamol and ascorbic acid can distort indicators laboratory tests (quantitative determination of glucose and uric acid in the blood plasma bilirubin, “liver transaminases *, LDG).
To avoid liver toxicity of paracetamol should not be combined with the admission of alcoholic beverages, as well as to make people prone to chronic alcohol consumption. The risk of liver damage increases in patients with alcoholic hepatosis.
Purpose of ascorbic acid in patients with rapidly proliferating tumor and metastatic intensively may increase during the process. In patients with high iron content in the body should be used ascorbic acid in minimal doses.
In one sachet honey-lemon contained 1,793 g of sugar, which corresponds to 0.15 XE.
One sachet contains chamomile 2,058 g of sugar, which corresponds to 0.17 XE.
Storage conditions
Storage temperature is 10-30 C.
Keep out of the reach of children!.
Dosing and Administration
Inside. Adults and children over 15 years: 1 sachet 2-3 times a sulei. The contents of the sachet to be completely dissolved in a beaker (200 ml) with warm water (50-60 ° C) and the resulting solution immediately drink. It is better to take the drug between meals. The maximum daily dose – 3 bags. The interval between doses of the drug should be at least 4 hours.
Patients with impaired renal or hepatic function in older patients and interval between doses of the drug should be at least 8 hours. duration of administration without consultation with a physician is not more than 5 days when administered as an analgesic and 3 days as an antipyretic.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist