Angidak sept rinse solution 150 ml 0.15%

Description

Composition
Active substance:
Benzydamine hydrochloride 1.5 mg
Excipients:
Ethanol 95% 80.84 mg
Glycerol (glycerin) 50.0 mg
Methyl parahydroxybenzoate 1.0 mg
Mint flavoring 0.3 mg
0.24 mg sodium saccharinate
Sodium hydrogencarbonate 0.11 mg
Polysorbate 20 0.05 mg
1 M sodium hydroxide solution or 0.5 M hydrochloric acid solution to pH 5.0-7.0
Water for injection ad 1 ml
Description:
Clear, colorless or slightly yellowish liquid with a characteristic odor of mint.
Product form:
Solution for topical application of 0.15%.
150 ml vials of a colorless or colored glass screw-cap the polymer with a protection mechanism by children or without protection mechanism by children.
1 bottle with dimensional polymeric cup having gradation, and instructions for use in a stack of cardboard.
Contraindications
– increased sensitivity to benzydamine or other components of the formulation;
– Children up to age 12 years.
Carefully
Increased sensitivity to aspirin or other nonsteroidal anti-inflammatory drugs, bronchial asthma (including history).
Dosage
1.5 mg / ml
Indications
Symptomatic therapy of oral pain and inflammatory diseases of upper respiratory tract (different etiology):
– gingivitis, glossitis, periodontitis, stomatitis (including after radiotherapy and chemotherapy);
– pharyngitis, laryngitis, tonsillitis;
– candidiasis of the oral mucosa (in combination therapy);
– calculous inflammation of the salivary glands;
– after surgery and trauma (tonsillectomy, mandible fractures);
– after treatment and extraction.
In infectious and inflammatory diseases requiring systemic treatment, it is necessary to use the drug in a combination therapy.
Interaction with other drugs
Studies of interaction with other drugs has not been performed.
Overdose
Currently, the cases of overdose have been reported.
Symptoms: The use of the preparation according to the instructions for use peredozirov-
ka unlikely. If accidentally ingested, the following symptoms medication: vomiting, abdominal cramps, anxiety, fear, hallucinations, seizures, ataxia, fever, tachycardia, respiratory depression.
Treatment: symptomatic; clear the stomach, causing vomiting or stomach wash, using a gastric tube (under medical supervision); provide medical supervision, maintenance therapy and the necessary hydration. The antidote is not known.
pharmachologic effect
Pharmacological group:
nonsteroidal anti-inflammatory drug.
Pharmacodynamics:
Benzydamine is a non-steroidal anti-inflammatory drug that belongs to a group of indazoles. Anti-inflammatory and local anesthetic effect, has an antiseptic effect against a broad spectrum of microorganisms, restores microcirculation. The mechanism of action of the drug associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis. Benzydamine has a specific antibacterial and antimicrobial action due to the rapid penetration through the membrane of microorganisms with consequent damage to cell structures, disturbance of metabolic processes and cell lysosomes.
It has an antifungal activity against Candida albicans. It causes structural modification of the cell wall of fungi and their metabolic chains thus prevents their reproduction, which was the basis for the use of benzydamine in inflammatory processes in the oral cavity, including infectious etiology.
Pharmacokinetics:
When applied topically, the drug is well absorbed through mucous membranes and penetrate into the inflamed tissue is found in blood plasma in an amount insufficient to produce systemic effects.
Excretion of the drug takes place mainly in the kidney as inactive metabolites or conjugation product.
Pregnancy and breast-feeding
It should not be used during pregnancy and lactation.
Conditions of supply of pharmacies
Without a prescription.
side effects
Classification of the incidence of adverse events according to the World Health Organization (WHO):
Very often -> 1/10.
Often – by> 1/100 to
Infrequently – by> 1/1000 to
Seldom – by> 1/10000 to
Very rarely –
The frequency is not known – can not be estimated from the available data.
In each group, undesirable effects are presented in order of decreasing seriousness.
Local reactions: rarely – dry mouth, burning sensation in the oral cavity; frequency is unknown – numbness in the oral cavity.
Allergic reactions: seldom – photosensitivity; rarely – hypersensitivity reactions,
skin rash, itching; very rarely – angioedema, laryngospasm; frequency is unknown – anaphylactic reaction.
If any of these instructions side effects are compounded, or observed any other side effects not mentioned in the instructions, you should immediately inform your doctor.
special instructions
When applying the solution the feeling of burning, the solution should be pre-diluted with water 2 times by adjusting the water level to the risks in a graduated cup.
In applying the drug may develop hypersensitivity reactions. In this case, it is recommended to discontinue treatment and consult a doctor for the appointment of appropriate therapy.
In a limited number of patients the presence of ulcers in the throat and mouth may indicate the presence of more serious disease. If symptoms persist for more than 3 days, you should consult with your doctor.
Use of the drug is not recommended in patients with hypersensitivity to aspirin or other nonsteroidal antiinflammatory drugs.
The drug should be used with caution in patients with bronchial asthma in history due to the development opportunities they bronchospasm in patients receiving the drug.
The preparation contains parahydroxybenzoates, which can cause allergic reactions.
Patients who exercise: when using preparations containing ethanol, doping of samples for the maximum allowable content of ethanol in the blood according to standards established by some sports federations can be positive. Drivers who drives a vehicle, it should be borne in mind that the preparation contains ethanol (in a single dose of the drug (15 ml) contained 1.15 g of ethanol).
The effect on the ability of control of vehicles and mechanisms
It does not affect the ability to drive vehicles and use machines.
Storage conditions
At temperatures above 25 ° C.
Keep out of the reach of children.
Dosing and Administration
Locally, the food. Adults (including elderly patients) and children 12 years of gargling or oral use of 15 ml of formulation (measuring cup attached) 2-3 times a day. After rinsing solution must be spit out. If the application of undiluted solution of a burning sensation occurs, the solution should be diluted (dilution added to the measuring cup 15 ml water). Do not exceed the recommended dose.
Duration of treatment 7 days; If after 7 days of treatment there is no improvement or there are new symptoms, you should consult with your doctor.
Use drug only according to the application and in those doses which are specified in the instruction. If necessary, consult your physician before using the drug.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist