Amiksin tab p / 60 mg of the film 10 pcs Pharmstandard

Description

Composition
Active substance:
1 tablet contains: tilorona – 60.0 mg or 125.0 mg.
Excipients:
Potato starch – 25,500 mg or 46,000 mg, microcrystalline cellulose – 60,000 mg or 120,000 mg, Povidone K30 (Kollidon 30) – 1,500 mg or 3,000 mg of calcium stearate – 1.500 mg or 3.000 mg of sodium croscarmellose (primelloza) – 1,500 mg or 3,000 mg; sheath: hypromellose (hydroxypropyl) -, or 3.4050 mg 6.8100 mg of titanium dioxide – 1.7815 mg or 3.5630 mg macrogol 4000 (polyethylene glycol 4000) – 0.4565 mg or 0.9130 mg polysorbate -80 (Tween-80) – 0.0570 mg or 0.1140 mg, dye quinoline yellow (E 104) – 0.1235 mg or 0.2470 mg, colorant sunset yellow (E 110) – 0.1765 mg or 0.3530 mg.
Description:
Antiviral immunostimulatory agent – interferon inducer of education.
Product form:
Tablets, film-coated 60mg, 125mg.
6 or 10 tablets in blisters; 6, 10 or 20 tablets per polymer jar. 1 or 2 blisters or 1 jar polymer together with instructions for use in a pile of cardboard.
Contraindications
Hypersensitivity to tilorona or any other component of the formulation. Pregnancy and breast-feeding. Children under the age of 7 years (dosage 60 mg), children up to 18 years (dosage 125 mg).
Dosage
60 mg
Indications
In the combined therapy
Children from 7 to 18 years: – for the treatment of influenza and other acute respiratory viral infections (ARI).
Adults (over 18 years): – the treatment of influenza and other acute respiratory viral infections; – the treatment of herpes infections;
Prevention of influenza and other acute respiratory viral infections in adults – in the complex therapy of infectious-allergic and viral.
Interaction with other drugs
Compatible with antibiotics and drugs traditional treatment of viral and bacterial diseases. Clinically significant interaction Amiksina® with antibiotics and traditional means of treatment of viral and bacterial diseases have been identified.
Overdose
Cases of overdose are not known.
pharmachologic effect
Pharmacodynamics:
The low molecular weight synthetic inducer of interferon, stimulates the formation in the body of all types of interferon (alpha, beta, gamma and lambda). Major producers of interferon in response to tilorona are intestinal epithelial cells, hepatocytes, T-lymphocytes, neutrophils, and granulocytes. After ingestion maximum production of interferon is defined in the sequence intestine – liver -. Bled 4-24 hours Amixin® possesses immunomodulatory and antiviral effect.
In human leukocytes induces the synthesis of interferon. Stimulates bone marrow stem cells, dose-dependently enhances antibody production, reduces the degree of immunosuppression, restores ratio T-suppressor and T-helper cells. It is effective against a variety of viral infections, including influenza virus, and other acute respiratory viral infections, hepatitis viruses and herpes viruses. antiviral mechanism of action is associated with inhibition of translation of virus-specific proteins in infected cells, resulting in suppressed reproduction of viruses.
Pharmacokinetics:
After intake of rapidly absorbed from the gastrointestinal tract. Bioavailability – 60%. About 80% of the drug is bound to plasma proteins. Displayed drug virtually unchanged through the gut (70%) and the kidneys (9%). The half-life (T1 / 2) -. Preparation 48 hours no biotransformation and does not accumulate in the body.
Pregnancy and breast-feeding
Use of the drug during pregnancy is contraindicated. If necessary, use during lactation should stop breastfeeding.
Conditions of supply of pharmacies
Without recipe.
side effects
Allergic reactions, dyspepsia, intermittent fever.
If any of these instructions side effects are compounded, or if you notice any other side effects not mentioned in the instructions, tell your doctor.
special instructions
The drug has no negative effect on the ability to drive vehicles and other classes of potentially hazardous activities that require high concentration and psychomotor speed reactions.
Storage conditions
In the dark place at a temperature not higher than 30 C.
Keep out of the reach of children.
Dosing and Administration
Amiksin taken orally after a meal.
For children from 7 to 18 years:
In uncomplicated forms of influenza and other acute respiratory viral infections – 60 mg 1 time a day on the 1st, 2nd and 4th day of treatment. Heading dose – 180 mg (3 tablets).
For adults:
For the treatment of influenza and SARS – 125 mg per day in the first 2 days of treatment followed by 125 mg every 48 hours. At Course – 750 mg (6 tablets).
For the prevention of influenza and other acute respiratory viral infections – 125 mg 1 time per week for 6 weeks. At Course – 750 mg (6 tablets).
For the treatment of herpes infection – the first two days of 125 mg, followed 48 hours later by 125 mg. Heading dose – 1.25-2.5 grams (10-20 tablets).
In the treatment of influenza and other acute respiratory viral infections in case of continued symptoms of the disease for more than 4 days, you should consult a doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist