Alpha-tocopherol acetate caps. 50% 100mg 10 pcs

Description

Composition
Active substance:
1 capsule contains: alpha-tocopherol acetate (vitamin E) 100 mg.
Excipients:
Sunflower oil 100 mg. capsule shell: Gelatin 44.73 mg Glycerol 14.67 mg methyl parahydroxybenzoate 0.29 mg, 0.31 mg dye azorubin.
Description:
Capsules spherical shape red oily liquid filled from light yellow to dark yellow in color, no rancid smell.
Product form:
Capsules 100 mg.
10 capsules in blisters.
1, 2, 3, 4, 6 blisters together with instructions for use placed in a stack of cardboard.
Contraindications
Increased individual sensitivity to the drug, acute myocardial infarction, childhood.
Carefully
Used in patients with severe cardiosclerosis, myocardial infarction, with an increased risk of thromboembolism; hypoprothrombinemia caused by deficiency of vitamin K.
Dosage
100 mg
Indications
Treatment and prevention of hypovitaminosis vitamin E.
Interaction with other drugs
Simultaneous administration of large doses of vitamin E to vitamin K or indirect anticoagulants (coumarin and indandione derivatives) increases the clotting time. Vitamin E increases the effect of corticosteroids, nonsteroidal antiinflammatory drugs, cardiac glycosides. When concomitantly with other vitamin and mineral preparations containing liposoluble vitamins A, D and E should consult a physician.
Overdose
When receiving vitamin E for a long period at doses of 400-800 IU / day: blurred vision, dizziness, headache, nausea, fatigue, diarrhea, gastralgia, asthenia.
When receiving more than 800 IU / day for a long period – an increase in the risk of bleeding in patients with hypovitaminosis of vitamin K, impaired metabolism of thyroid hormones, disorders of sexual function, thrombosis, thromboembolism, necrotizing colitis, sepsis, renal failure, bleeding in the retina, hemorrhagic stroke, ascites.
Treatment: symptomatic; removal of the drug; assignment glucocorticosteroids, vitamin E accelerating metabolism in the liver.
pharmachologic effect
Pharmacological group:
Vitamin.
Pharmacodynamics:
It has antioxidant activity involved in the biosynthesis of heme and protein, cell proliferation, tissue respiration and other important metabolic processes of the tissue; It protects tissues from the damaging effect of excessive amounts of free radicals and peroxidic products; It stimulates the synthesis of proteins and collagen.
Pharmacokinetics:
Absorption of duodenum 12 (requires the presence of bile salts, fats, normal functioning pancreas) – 20-40%. By increasing the degree of absorption of the dose decreases. Time to maximum concentration – 4 hr. Deposited in all organs and tissues, especially adipose tissue. Crosses the placenta, enters the breast milk. Excretion mainly through the gastrointestinal tract, the bile – more than 90%, less than 6% excreted by the kidneys in the form of glucuronides and other metabolites.
Pregnancy and breast-feeding
During pregnancy and breast-feeding taking this medication only on doctor’s advice.
Conditions of supply of pharmacies
Without recipe.
side effects
Allergic reactions (pruritus, redness of the skin); on the part of the gastrointestinal tract: diarrhea, nausea, gastralgia, dyspepsia.
special instructions
Do not exceed the recommended dosage. Do not take double the dose if you missed taking the drug.
Effects on ability to drive vehicles and management mechanisms
The drug does not affect the person’s ability to drive vehicles or machinery.
Storage conditions
In a dry, dark place at a temperature not higher than 25 ° C.
Keep out of the reach of children.
Dosing and Administration
The drug is intended only for receiving adult patients. 2 – 4 capsules a day for 1 – 2 weeks.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist