Afrin Moisturizing rhinitis by nasal spray, 15 ml., Bayer

$6.13

Afrin Moisturizing rhinitis by nasal spray, 15 ml., Bayer

Quantity:

SKU: 01607525447 Categories: , , Tags: ,

Description

Composition
Active substance:
Oxymetazoline hydrochloride 0.5 mg.
Excipients:
Microcrystalline cellulose and carmellose sodium (Avicel RC-591) 30 mg, 0.975 mg disodium hydrogen phosphate, sodium dihydrogen phosphate monohydrate 5.525 mg disodium edetate dihydrate 0.3 mg macrogol 1450 50 mg povidone K29-32 30 mg, benzyl alcohol 2 , 5 mg, 1.5 mg lemon flavor, benzalkonium chloride solution 17% 1,471 mg, 5 mg glycerol, purified water qs to 1 ml.
Description:
Afrin Moisturizing 15ml – Spray from rhinitis.
Afrin Moisturizing is advanced by means of rhinitis as a spray with a patented formula by which it is fixed to the nasal mucosa, nasal acting at the epicenter have from 1 minutes.
Afrin Moisturizing does not flow from the nose and does not flow into the throat, contributing to the removal of congestion since the first minute and facilitates nasal breathing.
Fixes an obstruction.
– Facilitates nasal breathing.
– Helps moisturize the nasal mucosa.
Afrin Moisturizing is indicated for the symptomatic treatment of:
– rhinitis (runny nose)
;
– allergic rhinitis;
– Sinusitis;
– Evstahiita;
– hay fever.
Distinctive features Afrin Moisturizing preparation are:
– Eliminates the symptoms of the common cold and allergic rhinitis, moisturizes dry and irritated nasal mucosa;
– Does not reduce the effectiveness of natural protection nose (1);
– Able to operate with 1 minute;
– Able to support its action up to 12 hours.
(1). Oxymetazoline in a concentration of 0.05% has no effect on the activity of ciliated epithelium. Zhang L et al. Effect of oxymetazoline on healthy human nasal ciliary beat frequency measured with high-speed digital microscopy and mucociliary transport time. Ann Otol Rhinol Laryngol 2008 Feb; 117 (2): 12733. ”
Product form:
0.05% nasal spray, nasal spray (chamomile) 0.05%. 15 ml in a tightly closed plastic opaque bottle with capacity of 23 ml with a dosing device and a fine spray protection cap, shrink wrapped to control the first opening with the company logo. 1 bottle in cardboard box, together with instructions for use.
Contraindications
Hypersensitivity to sympathomimetic means, to any component of the preparation, atrophic rhinitis, concurrent use of monoamine oxidase inhibitors (including the period of 14 days after their withdrawal), children under 6 years.
Carefully
Coronary artery disease, arrhythmias, congestive heart failure, expressed atherosclerosis, hypertension, hyperthyroidism, diabetes mellitus, chronic renal failure, angle-closure glaucoma, prostatic hyperplasia with clinical symptoms, pregnancy, lactation.
Dosage
0.5 mg / ml
Indications
Symptomatic therapy of rhinitis (common cold), allergic and / or inflammatory-infectious etiologies, sinusitis, evstahiit, hay fever.
Interaction with other drugs
Mestnoanesteziruyuschih slows the absorption of drugs, lengthens their actions.
The combined use with other vasoconstrictor drugs increases the risk of side effects.
With simultaneous use of monoamine oxidase inhibitors (including the period of 14 days after their withdrawal), and tricyclic antidepressants maprotiline – increase in blood pressure.
Overdose
When a large overdose or accidental ingestion possible: nausea, vomiting, cyanosis, fever, tachycardia, arrhythmia, increased blood pressure, dizziness, mental disorders, depression of the central nervous system (drowsiness, reduction of body temperature, bradycardia, decrease in blood pressure, respiratory arrest and coma).
Treatment – symptomatic. In case of accidental ingestion – gastric lavage, activated charcoal. Vasopressor drugs are contraindicated.
pharmachologic effect
Pharmacological group:
Decongestant agent – alpha-agonists.
Pharmacodynamics:
Alfa adrenostimuliruyuschee agent for topical administration. It has a vasoconstrictor effect. Oxymetazoline causes vasoconstriction mucous membranes of the nose, paranasal sinuses and eustachian tube, which leads to a reduction of swelling and release of nasal breathing in allergic and / or inflammatory-infectious rhinitis (common cold).
Due to the presence in the medicament excipients (microcrystalline cellulose and carmellose sodium, and povidone K29-32) Afrin® hydrating nasal spray does not flow from the nose and does not flow down into the throat, since after the administration into the nasal passages spray becomes more viscous and is retained the mucous membranes of the nose is more effective than standard aqueous solution.
This drug formulation comprises humectants (glycerol and macrogol 1450), promoting retention of moisture, which helps to ensure hydration of dry or irritated nasal mucosa.
According to clinical studies the drug begins to act for 1 minute and the action continues until 12 hours.
Pharmacokinetics:
When used as a nasal spray oxymetazoline hardly detected in the blood plasma.
Pregnancy and breast-feeding
Safety of the drug in pregnant women and during lactation has not been established, so the drug should be administered to pregnant or breast-feeding only on doctor’s advice if the expected benefits of the drug to the mother outweighs the potential risk to the fetus or infant.
Conditions of supply of pharmacies
Without recipe.
side effects
In general, the drug was well tolerated, and possible undesirable effects usually mild and transient.
Transient dryness and stinging of the nasal mucosa, dry mouth and throat, sneezing; increased blood pressure, increased anxiety, nausea, dizziness, headache, insomnia, palpitations, sleep disorders. With prolonged use – tachyphylaxis, reactive hyperemia and atrophy of the mucosa of the nasal cavity. Benzalkonium chloride, part of the drug may cause local skin reactions.
special instructions
Prolonged use (more than one week) possible return of symptoms of nasal congestion. If necessary, continue treatment over 5 days is necessary to consult with your doctor. Avoid getting product in eyes. Drug when used correctly and at recommended doses has no effect on driving vehicles and working with machinery, but in case of side effects such as dizziness, avoid these activities.
Storage conditions
At temperatures above 25 ° C. Keep out of the reach of children.
Dosing and Administration
Intranasally.
Before each use, need to vigorously shake the spray bottle.
Before the first use of a nasal spray is necessary to carry out its “calibrated” by pressing the sprayer head several times.
Adults and children over 6 years – 2-3 injections in each nostril at intervals of 10-12 hours. The multiplicity of applications can be increased to 3 times a day for adults. do not exceed this dose.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

Afrin

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