Aflyudol tab 100mg 20 pieces

$9.06

Aflyudol tab 100mg 20 pieces

Quantity:

Description

Composition
Active substance:
1 tablet contains: umifenovir hydrochloride monohydrate in terms of hydrochloride umifenovir – 0.1000 g ;.
Excipients:
Lactose monohydrate – 0.1722 g Povidone K-25 (polyvinyl pyrrolidone of middle) – 0.0064 g, crospovidone – 0.0094 g Colloidal silica (Aerosil) – 0.0090 g Magnesium stearate – 0.0030 g .
Excipients shell: Opadry II White [lactose monohydrate – 36%, hypromellose – 28% titanium dioxide – 26%, macrogol 4000 (polyethylene glycol 4000) – 10%] – 0.0120 g
Description:
Round biconvex tablets covered with a foil cover from white to white with cream tint colors, rough, on the fracture from white to white to greenish or yellowish cream color.
Product form:
Film-coated tablets 50 mg or 100 mg, Valium planimetric packaging.
Packaging 10,20 or 30 tablets.
Contraindications
Hypersensitivity to umifenovir or any component of the drug, lactase deficiency, lactose intolerance, glucose-galactose malabsorption, children up to 3 years.
Dosage
100 mg
Indications
Prevention and treatment in adults and children:
– A and B flu, SARS, severe acute respiratory syndrome (SARS) (including complicated bronchitis, pneumonia);
– the treatment of chronic bronchitis, pneumonia, and recurrent herpetic infection.
Prevention of postoperative infectious complications and the normalization of immune status.
Combined therapy of acute intestinal infection rotavirus etiology in children older than 3 years.
Interaction with other drugs
In the appointment of other drugs, negative effects were noted.
Overdose
It is not checked.
pharmachologic effect
Pharmacological group:
Other antiviral drugs.
Pharmacological properties:
An antiviral agent.
Pharmacodynamics:
An antiviral agent. Specifically inhibits the influenza viruses A and B, coronavirus associated with severe acute respiratory syndrome (SARS). According to the mechanism of the antiviral action relates to inhibitors of fusion (fusion), interacts with hemagglutinin of the virus and prevent fusion of lipid shell of a virus and cellular membranes. It has moderate immunomodulatory effects. Possesses interferon-inducing activity, stimulating humoral and cellular immune response, the phagocytic function of macrophages, increases resistance to viral infections. Reduces the incidence of complications associated with viral infection, as well as exacerbation of chronic bacterial diseases.
Therapeutic efficacy for viral infections manifest in reducing the severity of intoxication and clinical phenomena, reduction of duration of the disease, reducing the risk of complications.
It refers to preparations of low toxicity (LD50> 4 g / kg). It does not have any negative impact on the human body when administered orally in the recommended dosages.
Pharmacokinetics:
Absorption – fast. Rapidly distributed to organs and tissues. Time to maximum concentration when taking a dose of 50 mg – 1.2 hours at a dose of 100 mg -. 1.5 h metabolized in the liver. The half-life is 17-21 h. About 40% is excreted unchanged, primarily in the bile (38.9%) and the minor kidneys (0.12%). During the first day shows 90% of the administered dose.
Conditions of supply of pharmacies
Without recipe.
side effects
Rarely – allergic reactions.
special instructions
Shows no central neurotropic activity and can be used in medical practice as a preventive measure in healthy persons of various professions, including those requiring special attention and coordination of movements (transport drivers, operators, etc.).
Storage conditions
At a temperature not exceeding 25 C. Keep out of reach of children.
Dosing and Administration
Inside, before meals. Single dose: children from 3 to 6 years – 50 mg, from 6 to 12 – 100 mg, over 12 years and adults – 200 mg (2 tablets of 100 mg or 4 tablets of 50 mg).
For nonspecific prevention:
– in direct contact with patients with influenza and other ARI: children from 3 to 6 years – 50 mg, from 6 to 12 – 100 mg, over 12 years and adults – 200 mg 1 time per day for 10-14 days;
– during the epidemic of influenza and other acute respiratory viral infections, for the prevention of exacerbations of chronic bronchitis, recurrent herpetic infection: children from 3 to 6 years – 50 mg, from 6 to 12 years – 100 mg, over 12 years and adults – 200 mg 2 times a week for 3 weeks.
– for the prevention of SARS (in contact with the patients): adults and children over 12 years prescribed 200 mg once a day for 12-14 days.
– prevention of postoperative complications: children from 3 to 6 years – 50 mg, from 6 to 12 years – 100 mg, over 12 years and adults – 200 mg for 2 days before surgery, then 2-5 days after surgery.
For the treatment of:
– influenza, SARS without other complications: children from 3 to 6 years – 50 mg, from 6 to 12 – 100 mg, over 12 years and adults – 200 mg 4 times a day (every 6 hours) for 5 days;
– influenza, other SARS with the development of complications (bronchitis, pneumonia and others.): Children from 3 to 6 years – 50 mg, from 6 to 12 – 100 mg, over 12 years and adults – 200 mg 4 times a day (every 6 hours) for 5 days then 1 single dose once weekly for 4 weeks.
Severe acute respiratory syndrome (SARS): adults and children over 12 years – 200 mg 2 times a day for 8-10 days.
In the complex treatment of chronic bronchitis, herpes virus infection:
children from 3 to 6 years – 50 mg, from 6 to 12 – 100 mg, over 12 years and adults – 200 mg 4 times a day (every 6 hours) for 5-7 days, followed by a single dose of 2 times a week for 4 weeks.
Combined therapy of acute intestinal infections rotavirus in children over three years of age: children from 3 to 6 years – 50 mg, from 6 to 12 – 100 mg, over 12 years – 200 mg 4 times a day (every 6 hours) for 5 days.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

TATHIMFARM

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