Afloderm Cream 0.05% 20g tube

Description

Composition
Active substance:
1 g of cream contains: alclometasone dipropionate – 0.500 mg ;.
Excipients:
Propylene glycol – 250.00 mg, hlorokrezol – 1.00 mg sodium dihydrogen phosphate dihydrate – 2,995 mg, phosphoric acid – 0,040 mg, cetostearyl alcohol [60% cetyl alcohol, stearyl alcohol 40%] – 72.00 mg macrogol tsetostearat – 22 50 mg macrogol glyceryl – 30.00 mg, white soft paraffin – 210,00 mg sodium hydroxide – qs, purified water – 410.960 mg.
Description:
Uniform cream white.
Product form:
Cream for external use 0.05%
At 20 and 40 g of the cream in aluminum tubes. The opening of the tube is protected by a membrane. Tube closed with a polyethylene cap with a punch to the membrane. Each tube is placed in a cardboard box with instructions for use.
Contraindications
Hypersensitivity to alclometasone or any of the auxiliary components of the formulation; lupus, cutaneous manifestations of syphilis, chickenpox, viral skin infection, post-vaccination reactions skin, open wounds, trophic ulcers, rosacea, acne vulgaris; children’s age (up to 6 months).
Dosage
0.05%
Indications
Dermatoses and inflammatory skin disorders that respond to therapy with topical glucocorticosteroids (including eczema, atopic dermatitis, allergic and contact dermatitis, including fitodermatit, psoriasis, photodermatitis and sunburns, allergic reactions to insect bites).
Afloderm® cream used for the treatment of acute and subacute stages of inflammatory diseases of the skin including accompanied by exudation.
Afloderm® cream is recommended for the treatment of inflammatory diseases of the skin on the delicate and sensitive parts of the body (face, neck, breasts, genital area) and extra hydration needs of the affected skin, which is carried out by base components of the preparation.
Interaction with other drugs
Interactions with other drugs known.
Overdose
Symptoms: the development of systemic side effects of corticosteroids. Treatment: symptomatic.
pharmachologic effect
Pharmacological group:
Glucocorticosteroids for local use.
Pharmacological properties:
Glucocorticosteroids for external use of mild to moderate activity. It has anti-inflammatory, antipruritic and vasoconstrictive action. The mechanism of anti-inflammatory action is completely unclear. It is believed that alclometasone induces the synthesis of a phospholipase A2 inhibitor (lipokortinov). As a result, it decreases the release of arachidonic acid from membrane phospholipids. This leads to the inhibition of synthesis of prostaglandins and leukotrienes (inflammatory mediator) from arachidonic acid.
Pharmacokinetics:
Absorption through the skin depends on several factors (including the type of dosage form and integrity of the skin). And other inflammatory diseases of the skin can increase absorption. In healthy volunteers for 8 hours absorbed 3% alclometasone.
Pregnancy and breast-feeding
Pregnancy
Use of the drug in pregnant cream Afloderm® allowed. In these cases, the application must be carried out under the supervision of a physician, be brief and limited to small areas of the skin. Data on the teratogenic effects are absent.
Breast-feeding
Perhaps the use of the drug Afloderm® cream in nursing mothers. Maintain the following precautions when using the drug in nursing mothers, in particular, the preparation should not be applied on the skin of the breast before feeding.
Conditions of supply of pharmacies
Without recipe.
side effects
Usually the drug is well tolerated. Side-effects when applied externally alclometasone are rare and are reversible.
For the skin: with a frequency of 1% – itching, burning, erythema; -follikulit infrequently, akneiformnaya rash, hypopigmentation, perioral dermatitis, dermatitis, secondary infection, skin atrophy, striae, miliaria.
In the case of giperchuvstvitelnosti reactions or side effects of therapy should be discontinued and consult a doctor !.
special instructions
Avoid contact with the eyes of the drug (due to the possible development of glaucoma and cataracts), as well as the open wound surface. If the disease is complicated by the development of secondary bacterial or fungal infection to drug therapy Afloderm® need to add an antibacterial or antifungal agent.
Effects on ability to drive vehicles and mechanisms:
Data on the effects of the drug Afloderm® on ability to drive and there are no mechanisms.
Storage conditions
At a temperature of not higher than 30 ° C. Keep out of the reach of children!.
Dosing and Administration
For external use only.
Cream Afloderm® uniformly applied thinly to the affected areas of skin 2-3 times a day. In children and in the period of follow-up care may use the drug once a day. For the prevention of relapse in the treatment of chronic illness therapy should be continued for some time after the disappearance of all symptoms.
Afloderm® drug can be used in children from the sixth month of life. Be aware that small children skinfolds and synthetic diapers can have an effect similar to the effect of occlusive dressings, and to increase the resorption of the active ingredient of the drug. Furthermore, children can have a greater degree of systemic resorption because of the relation between the surface skin and body weight, as well as due to insufficient skin maturity. Do not apply under an occlusive dressing in the contact points between the diapers and diapers with the skin. The maximum duration of treatment in children – 3 weeks. Long-term use of the drug should be taken only under medical supervision.
If no effect should clarify the diagnosis for 2 weeks.
When passing the acute period of the disease, if necessary, use of the drug in the most dense parts of the skin (hands, feet), especially at elevated dryness, and if necessary, the manifestation of anti-inflammatory drug effect in deeper layers of the skin is appropriate transition to the use of the preparation in the form Afloderm® ointment.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist