80mg / 2ml amp Artrozilen ml injection piece 6

$3.81

80mg / 2ml amp Artrozilen ml injection piece 6

5 in stock

Quantity:

Description

Composition
Active substance:
ketoprofen lysine salt – 80 mg;
Excipients:
Sodium hydroxide, Citric acid, water for injection.
Description:
The clear, colorless to slightly yellowish solution.
Product form:
2 ml vial dark glass (glass hydrolytic type 1 Eur. Pharm.). 6 ampoules pallet of plastic. One pallet in a cardboard box with instructions for use.
Contraindications
Hypersensitivity (including to other. NSAIDs), “Aspirin” asthma, gastric ulcer and duodenum 12 (exacerbation), ulcerative colitis (exacerbation), Crohn’s disease, diverticulitis, peptic ulcer, hemophilia and others. Coagulation disorders blood, chronic renal failure, children’s age (18 years), pregnancy, lactation.
Precautions – anemia, bronchial asthma, alcoholism, smoking, alcoholic cirrhosis, hyperbilirubinemia, hepatic failure, diabetes, dehydration, sepsis, chronic heart failure, edema, hypertension, blood diseases (including leukopenia), deficiency of glucose-6 -fosfatdegidrogenazy, disease, old age.
Dosage
80 mg / ml
Indications
For short-term treatment of acute pain syndrome: diseases of the musculoskeletal system of various origins; post-operative pain; post-traumatic pain, and pain associated with inflammation.
Interaction with other drugs
Inductors microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, flumetsinol, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of active hydroxylated metabolites.
Reduces the efficiency of uricosuric drugs, enhances the action of anticoagulants, antiplatelet agents, fibrinolytics, ethanol mineralkortikosteroidov side effects, glucocorticoids, estrogens. Reduces the effectiveness of antihypertensive and diuretics.
Co-administration with other. NSAIDs, corticosteroids, ethanol, corticotropin may lead to the development of ulcers and gastrointestinal bleeding, increase the risk of renal functions.
Simultaneous with the appointment of oral anticoagulants, heparin, thrombolytics, antiplatelet, tsefaperazon, cefamandole and tsefotetanom increases the risk of bleeding.
Increases hypoglycemic effect of insulin and oral hypoglycemic agents (requires recalculation of the dose).
Co-administration of sodium valproate causes disturbance of platelet aggregation. Increases concentration of plasma verapamil and nifedipine, lithium preparations methotrexate.
Overdose
Currently, the cases of drug overdose Artrozilen were reported. In case of overdose requires monitoring of respiratory and cardiac function. Specific antidote does not exist. If necessary, should be symptomatic therapy. Hemodialysis is ineffective.
pharmachologic effect
Pharmacological group:
Nonsteroidal anti-inflammatory drug (NSAID).
Code: M01AE03
Pharmacodynamics:
It has anti-inflammatory, analgesic and antipyretic effect. Inhibiting cyclooxygenase type I and II, inhibits the synthesis of prostaglandins. Antibradikininovoy possesses activity stabilizes lysosomal membranes and inhibits the release of these enzymes that contribute to tissue destruction in chronic inflammation. It reduces the release of cytokines, inhibits the activity of neutrophils. Reduce morning stiffness and swelling of joints, increases range of motion.
Ketoprofen lysine salt, as opposed to ketoprofen, anti-inflammatory, my molecule with a neutral pH and almost no irritation to the gastrointestinal tract.
Pregnancy and breast-feeding
Like other NSAIDs, Artrozilen should not be used in the I trimester of pregnancy. Use of the drug in the I and II trimester should be closely monitored by the attending physician. Breast-feeding while using this drug should be discontinued.
Conditions of supply of pharmacies
On prescription
side effects
Gastrointestinal tract: abdominal pain, diarrhea, duodenitis, erozivnoyazvennye lesions of the gastrointestinal tract, gastritis, gematomezis, esophagitis, stomatitis, melena.
Liver: increase in bilirubin, increase in “liver” enzymes, hepatitis, hepatic failure, enlarged liver.
Nervous system: dizziness, hyperkinesia, tremor, vertigo, mood swings, anxiety, hallucinations, irritability, malaise
Senses: conjunctivitis, blurred vision.
Skin: urticaria, angioedema, erythematous rash, itching, makulo-papular rash, increased sweating, erythema multiforme (including Stevens-Johnson syndrome).
Urogenital: painful urination, cystitis, edema, hematuria, menstrual disorders.
Forming Organs: leykotsitopeniya, leukocytosis, lymphangitis, decrease of prothrombin time, purpura, thrombocytopenia, thrombocytopenic purpura, an increase in size of the spleen, vasculitis.
Respiratory system: bronchospasm, dyspnea, throat feeling spasm, laryngospasm, laryngeal edema, rhinitis.
Cardiovascular system: hypertension, hypotension, tachycardia, chest pain, syncope, peripheral edema, pallor.
Allergic reactions: anaphylactoid reactions, swelling of the mouth, throat edema, periorbital edema.
special instructions
During treatment requires monitoring picture peripheral blood and functional state of the liver and kidneys.
If necessary, definition of 17-ketosteroids drug should be discontinued 48 hours before the study.
Acceptance of ketoprofen may mask signs of infection.
If the kidney and liver functions necessary to decrease the dose and careful observation. Use of ketoprofen patients suffering from bronchial asthma, can lead to attacks of bronchial asthma.
Women planning a pregnancy should refrain from using the drug as may reduce the likelihood of implantation of the egg.
Impact on the ability of management and road machinery
During the period of the drug should refrain from potentially dangerous activities associated with the need to concentration and rapid psychomotor reactions.
Storage conditions
At temperatures above 25 ° C, protected from light. Keep out of the reach of children.
Dosing and Administration
1 ampoule per day intramuscularly or intravenously. The maximum dose of 1 ampoule 2 times per day. Intravenous administration of the drug is allowed only in a hospital. The drug is used for treatment of short – up to 3 days. If necessary, further use of the drug is recommended to switch to reception of oral dosage forms or suppositories. In elderly patients, use no more than 1 mg per day.
Ampoules should be opened at a special line of fracture. After opening the ampoule solution is used immediately.
Aqueous solutions of ketoprofen lysine salt can be used for physiotherapeutic treatment (iontophoresis, mesotherapy): the iontophoresis solution is applied to the negative pole.
For intravenous use, slow infusion is recommended for increasing the time of action of the drug. Artrozilena infusion solution is prepared on the basis of 50 or 500 ml of the following aqueous solutions: 0.9% chloride, 10% aqueous solution of sodium levulose, 5% aqueous dextrose solution, Ringer’s acetate, Ringer’s lactate (Hartmann), a colloidal solution of dextran 0.9% sodium chloride solution or 5% glucose solution. Dilution Artrozilena in solution a small volume (50 ml) was injected into the drug / bolus.
In solutions of large volume (500 ml) infusion duration not less than 30 minutes.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist

Additional information

Weight0.100 kg
Manufacturer

SI ES SI LTD

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