1% Diclofenac Gel 40g tube Hemofarm

Description

Composition
Active substance:
1 g of gel contains 11.60 mg of diclofenac diethylamine (respectively sodium diclofenac 10 mg).
Excipients:
Isopropanol, carbomer 940, polysorbate 80, benzyl alcohol, sodium disulfite, sorbitol, trolamine, purified water.
Description:
The clear, colorless homogeneous gel.
Product form:
Gel for external application of 1%.
40 g of the gel in an aluminum tube, sealed with a screw cap made of plastic. The opening of the tube is protected by an aluminum membrane. The cap is a monolithic structure, including a device for piercing the membrane. The tube together with instructions for use placed into cardboard pack.
Contraindications
Hypersensitivity to diclofenac or other ingredients, acetylsalicylic acid or other NSAIDs. Full or partial combination of asthma, recurrent nasal polyposis and paranasal sinuses and intolerance to acetylsalicylic acid or other NSAIDs (history). Pregnancy (III trimester), lactation, infancy (up to 12 years), impaired skin integrity.
Dosage
1 %
Indications
Inflammatory and degenerative diseases of the musculoskeletal system (rheumatoid arthritis, psoriatic, juvenile chronic arthritis, ankylosing spondylitis, rheumatic soft tissue, gouty arthritis); traumatically caused by inflammation of tendons, ligaments, muscles and joints (due to sprains, bruises and under a load).
Interaction with other drugs
The drug can increase the effects of drugs that cause photosensitization.
Clinically significant interactions are not described with other drugs.
Overdose
Symptoms due to low systemic absorption when the gel applications, overdose unlikely. In case of accidental ingestion may develop systemic side effects. Treatment: gastric lavage, induction of vomiting, activated charcoal, forced diuresis, symptomatic therapy. Dialysis is not effective due to high degree of protein binding of diclofenac (about 99%).
pharmachologic effect
Pharmacological group:
Non-steroidal anti-inflammatory agent.
Pharmacological properties:
Non-steroidal anti-inflammatory agent, a derivative of phenylacetic acid, anti-inflammatory and analgesic action. Non-selectively inhibiting cyclooxygenase-1 (TSOG1) and cyclooxygenase 2 (TSOG2) acts on the metabolism of arachidonic acid, prostaglandins decreases the amount (Pg) in inflammation.
Pharmacokinetics:
When applied topically partially absorbed through the skin, bioavailability – 6%. Relationship to plasma proteins – 99,7%. Excreted by the kidneys. In patients with polyarthritis receiving topical therapy (in the inflamed joint) concentration in synovial fluid and tissue is higher than the concentration in plasma.
Pregnancy and breast-feeding
Application of pregnancy (III trimester) and lactation – is contraindicated.
Conditions of supply of pharmacies
Without recipe.
side effects
For the skin eczema, photosensitivity, contact dermatitis (itching, redness, swelling the treated skin area, papular, vesicular rash, desquamation).
Allergic reactions (itching and skin burning, erythematous rash, urticaria, angioedema, systemic anaphylactic reactions (including shock).
special instructions
The gel is applied only to undamaged skin. After applying should not apply an occlusive dressing.
When applied to a large surface of the skin increases the risk of developing long-term systemic side effects.
Avoid exposure of drug in the eyes, mucous membranes or open wounds. Use only as an external agent.
Storage conditions
At a temperature of 15 to 25 ° C.
Keep out of the reach of children!.
Dosing and Administration
Outwardly. Adults and children over 12 years of drug applied in a thin layer over the fire of inflammation 3-4 times a day and gently rubbed. The required amount of the drug depends on the size of the painful area. Single dose: 2 – 4 g (which is comparable in volume to the size of large cherries).
After applying the drug to wash hands.
The duration of treatment depends on the indication and therapeutic effect. After 2 weeks of use of the drug should consult a doctor.
Information
Appearance may differ from that depicted in the picture. There are contraindications. You need to read the manual or consult with a specialist